Protein Alignment CG10804 and SLC6A14

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_009162.1
• Gene: SLC6A14 / 11254
• HGNCID: 11047
• Length: 642
• Species: Homo sapiens
• Alignment Length: 639
• Identity: 229/639 - (35%)
• Similarity: 345/639 - (53%)
• Gaps: 106/639 - (16%)

  Fly   102 SADQQDIVEGEK-EGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLC 165
            ||..::...||. |.::|.:|..|..:||:.||||||||||||||||...|||||||:||.|||.
Human    19 SASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLA 83

  Fly   166 IQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSF 230
            :.|:|:|:||.::||....|.:.|| ::.|...|:||:..::|..|.:|||.|||:.|.|:..||
Human    84 LAGLPLFFLECSLGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASF 147

  Fly   231 ESPLPWADCPTRLYK----------------------------------NFTYDHEPECVASS-- 259
            :|.|||.:|.:...|                                  |||      |:..|
Human   148 QSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFT------CINGSEI 206

  Fly   260 ------PTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIF 318
                  |::.||.:..||.|..::......:::|:.|:::|.:|...:.:||.||||:||.||:|
Human   207 YQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALF 271

  Fly   319 PYVVLIIFFFRGITLKGAADGVAHLF--TPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSY 381
            |||||:|...||.||:||:.|:::..  ...:..|.:..||.:|.||||:||.:|:|||:|.|||
Human   272 PYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSY 336

  Fly   382 NPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDL 446
            |...|||:.|||:|.||||.||:|||..:||::|..|..:    .:|.:.:|
Human   337 NKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHIS----GKEVSQVV------------- 384

  Fly   447 QTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFP 511
                   .||..||||.:.||:.|.||...|::|||.||.|||:||||.::|.:.|::.|  |||
Human   385 -------KSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQD--LFP 440

  Fly   512 NLPKEYIVGALCFSCCTI----SMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVR 572
            .:.|:..| .:...||.:    .:.....||.|...|:|.|...:.:||.|:.|.:.|.:|||..
Human   441 KVMKKMRV-PITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGN 504

  Fly   573 RFSDDIEMMTGSRPNFYWMF---CWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGATEGME 634
            ||.:|.|||.|::...:|::   ||..::|..::.|.:.|..|.  ...:|.|          :.
Human   505 RFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQF--HRPNYGA----------IP 557

  Fly   635 WPHWCIVVAFFLILSSILWIPIVAVLRLCGIK------VVEDSDPA--WFPEAE 680
            :|.|.:.:.:.:|:..|:||||:|::::...|      ::....||  |.|..|
Human   558 YPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLE 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	217/591 (37%)
SLC6A14	NP_009162.1	SLC6sbd_ATB0	36..641	CDD:271391	224/622 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..642

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810