DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10804 and si:ch211-132b12.3

DIOPT Version :9

Sequence 1:	NP_001138150.1	Gene:	CG10804 / 31317	FlyBaseID:	FBgn0029663	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001076419.1	Gene:	si:ch211-132b12.3 / 100002232	ZFINID:	ZDB-GENE-050419-161	Length:	577	Species:	Danio rerio

Alignment Length:	575	Identity:	228/575 - (39%)
Similarity:	315/575 - (54%)	Gaps:	64/575 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 VEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPY--FIMLCIQGIPI 171
            ::|:.  |||..|..|..||||..|..||:|||||||||..:||||.||:||  |:|.|  |:|:
Zfish     4 IKGQT--EERGFWGRKAEFLLAVAGNVVGVGNVWRFPYLCYRNGGGVFLIPYLVFVMTC--GVPL 64

  Fly   172 FYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPW 236
            |.||..:||...:|.|..|..:.|...|:|.:..::.....:|:..|:||.|.||:.||.|.|||
Zfish    65 FLLETVMGQFTHEGGITCWHLLCPLAQGVGYAGQLIELYSCMYFTIILAWALFYLIFSFSSQLPW 129

  Fly   237 ADCPTRLYK----------NFTYDHEPECVASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALI 291
            |.| ..::.          |.|::...:..::|....:|.|..|..|..::.....|:.:|:.|.
Zfish   130 ASC-DNIWNTDNCVNLAAGNLTFNRTTQINSTSAATEFWERRVLSLSGGIEEIGKINWEIALCLF 193

  Fly   292 VSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVV 356
            |.|.:.|.|:.:|:.|:||:||.||.||||:|::...||:||.||..||.....|....|.||.|
Zfish   194 VMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYPEPAHLADPQV 258

  Fly   357 WLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATAT 421
            |:|||||:|||..|..|.|||..|||..:||||||:..:.|.|.|||..||..||||:||.|
Zfish   259 WMEAGTQVFFSYSLCSGILIALGSYNQYSNNCYRDSFWLCLLNSGTSFVAGFAVFSVLGFMA--- 320

  Fly   422 FDRCTEERNGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLF 486
                           ....:||    .|:|.  ||.|||||.:.:|:...|..|||||.||:|:.
Zfish   321 ---------------HVQGVPV----EEVAE--SGPGLAFIAYPQAVAMMPFPQLWAVCFFIMII 364

  Fly   487 TLGIDSQFGTLEGVVTSLVDMKLFPNL-----PKEYIVGALCFSCCTISMCFANGAGSYIFQLMD 546
            .||:||||..:|.||||:.|  |||.:     .:|..|..||.:|....:......|.|:|||.|
Zfish   365 LLGLDSQFVAMECVVTSVTD--LFPEVLRRAGRRELFVLLLCLTCFFGQLIMVTEGGMYVFQLFD 427

  Fly   547 SFAGNFP-LLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYLSPCAMVTILLASF 610
            ::|.|.. .|.:::||.|:|.:|:|..:..|.|:.||.||||:::|.|||||:|...:|..:.|.
Zfish   428 NYASNGACFLFLSVFESLTIGWIFGAEKMFDIIKDMTESRPNYWFMLCWKYLTPLVSLTSFVYSM 492

  Fly   611 --YQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIVAVLRLC 663
              |..||    |..|         ..:|.|..|:.:.|.|||||.:|..|:.::|
Zfish   493 VRYTPLT----YNRW---------YVYPDWAHVLGWLLALSSILLVPGWALGQMC 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	223/560 (40%)
si:ch211-132b12.3	NP_001076419.1	SLC6sbd-TauT-like	11..550	CDD:271387	225/566 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810