DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12206 and Grxcr2

DIOPT Version :9

Sequence 1:	NP_570060.1	Gene:	CG12206 / 31316	FlyBaseID:	FBgn0029662	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001028598.1	Gene:	Grxcr2 / 332309	MGIID:	2685697	Length:	254	Species:	Mus musculus

Alignment Length:	187	Identity:	48/187 - (25%)
Similarity:	72/187 - (38%)	Gaps:	37/187 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 RNGVATFLQLQQPNVKNYMEK--------DVGKVVLYTTSMGIIRDTYAKCANVKKILRTLLIKF 466
            |:..|..|...||...:|...        |.||:::||.::.|||....|...::|||:...:.
Mouse    89 RDSGAYTLAGSQPLFNDYKANDHKPPPIIDFGKIIIYTNNLKIIRTPMDKRDFMRKILQKEDVA- 152

  Fly   467 EERDIFMSVEYQQE------MRERMQDETIRVPQLFVEGQLIGDANIVERLNESGELRQLLRPYK 525
            ||..:.::.|...:      :.||.........:.|:..|...|..:.|
Mouse   153 EEASLMITGENDGDREQGCPLPERNGSPLPESERTFLHSQHTQDGLVPE---------------- 201

  Fly   526 SIATAYTCQTCGGYRMLPCPACNGSKKSMHRNHFTAEFVALKCMNCDEVGLIKCPNC 582
                  .|..|.|..:..|..|:|||.||..|.|...:.||:|..|:|.||..|..|
Mouse   202 ------DCLHCQGSGIATCSLCHGSKFSMLANRFKESYRALRCPACNENGLQPCRIC 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12206	NP_570060.1	GRX_GRX_like	434..579	CDD:239329	38/150 (25%)
Grxcr2	NP_001028598.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..183		3/21 (14%)
		Thioredoxin_like	<200..249	CDD:294274	20/70 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2824
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700