Protein Alignment CG16781 and MARCHF5

DIOPT Version :9

• Sequence 1: NP_001259211.1
• Gene: CG16781 / 31315
• FlyBaseID: FBgn0029661
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_060294.1
• Gene: MARCHF5 / 54708
• HGNCID: 26025
• Length: 278
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 123/291 - (42%)
• Similarity: 173/291 - (59%)
• Gaps: 30/291 - (10%)

  Fly    41 ERICWICFATSEDNPHAHWVQPCQCRGDTKWVHQSCLYRWIDEKQLGDRRQTVICQQCQTEYIMV 105
            :|.||:||||.||:..|.||:||:|||.||||||:||.||:||||.|:....|.|.||..||::|
Human    11 DRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIV 75

  Fly   106 FPQMNPIARVLEKLDYAVRRICPFLVLGMFLCCIYWIALTYGAFTIIQVVGQDRAMQLME--NKV 168
            ||::.|:..||:..|..:.:.|||...|:.:..|||.|:||||.|::||||....:.:||  :.:
Human    76 FPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPL 140

  Fly   169 ILLVGLPFIPVGLILFRLVRWKDAVLKAMRSIYIYIPRKLPFFHRTNQSEGASRDLGDLGDLDDL 233
            .||:|||.|||.|||.:::||:|.||:..|.    ...||...:
Human   141 FLLIGLPTIPVMLILGKMIRWEDYVLRLWRK----YSNKLQILN--------------------- 180

  Fly   234 SVSSSSSISLP--PIQHNPSITEPFYISRLICGAFFLPTFATTVGNVFFGRLDDALQRTILGGIA 296
            |:.......:|  |.:.|| :.:....:|::|||...||.||.||.:.|..::..||||||||||
Human   181 SIFPGIGCPVPRIPAEANP-LADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIA 244

  Fly   297 YIGIKGLLKMYLDQKLYLRRLGRCILNYTDE 327
            ::.|||..|:|..|:.|||:..|.||||.::
Human   245 FVAIKGAFKVYFKQQQYLRQAHRKILNYPEQ 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16781	NP_001259211.1	RINGv	43..99	CDD:128983	34/55 (62%)
MARCHF5	NP_060294.1	RING_CH-C4HC3_MARCH5	12..72	CDD:319615	36/59 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153120
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6573
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1210654at2759
OrthoFinder	1	1.000	-	-		FOG0003968
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104806
Panther	1	1.100	-	-	O	PTHR46283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X270
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.660