DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10801 and kel-3

DIOPT Version :9

Sequence 1:	NP_570058.1	Gene:	CG10801 / 31314	FlyBaseID:	FBgn0029660	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_499784.2	Gene:	kel-3 / 176775	WormBaseID:	WBGene00002185	Length:	591	Species:	Caenorhabditis elegans

Alignment Length:	288	Identity:	69/288 - (23%)
Similarity:	116/288 - (40%)	Gaps:	57/288 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 NEIMWKATKMCWFDDLEIQIESRFFFVSHILFT----YF---------ARNFRKISSQFLQMPVQ 243
            ||:..|    |...|:.:.:|:|......::..    ||         ..|.::|:.:...|..:
Worm    42 NELRSK----CQLCDVALLVENRKLSAHKVILAATIPYFRGMFTLDLMEANMKEINIEDSDMNYE 102

  Fly   244 KIDMAVLIRIYEWML----NEEKTFVVGQNLISFYAAAHWLGVHQLIKQAWSTFSADGVYDIWEI 304
            .:| |:|...|...|    :..::.::|.|...........|...|.:...|  :|..:.:..::
Worm   103 TVD-ALLSFAYTGELRITTSNVQSIMLGANFFQMLEVVQHCGNFLLTRLHPS--NALSIREFCKM 164

  Fly   305 NAFQAYI--MAKDYRCPEIMIVMQSRLRKCFLPIVASWEFLEFDVNEVTTLLEQDMLCVNSEDEI 367
            ...:..|  |..||            ::|.|:.:....:|....:.:...||..|.|.|:||:::
Worm   165 MCVEEKITEMTDDY------------IQKHFMAVSKDEDFKRLSLEDAIELLRNDHLYVDSEEQV 217

  Fly   368 FFAVFHWLNYSWTERKKHAVKVMQKVRFGLLSPWLRRSIC--------NMPENDRIGEIGQ---L 421
            :.|...|||.. ..|.:.|.|::..||..||||....||.        ::|..|.|.|...   |
Worm   218 YVAAMEWLNCD-VIRHEQAAKILPCVRLPLLSPTYLSSIVASNPIIKKDIPCRDLIDEAKDYHLL 281

  Fly   422 PEICSLI--WEGT-LLCQ----AIIAIG 442
            |:..|||  ::.| .|||    .|:|||
Worm   282 PDRRSLIKSFKCTPRLCQIVPGLIVAIG 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10801	NP_570058.1	BACK	306..401	CDD:285009	26/96 (27%)
CG10801	NP_570058.1	DUF4734	418..512	CDD:292506	13/35 (37%)
kel-3	NP_499784.2	BTB_POZ	32..149	CDD:365784	21/111 (19%)
		PHA03098	51..568	CDD:222983	65/275 (24%)
		KELCH repeat	341..384	CDD:276965
		KELCH repeat	388..431	CDD:276965
		KELCH repeat	435..479	CDD:276965
		KELCH repeat	482..527	CDD:276965
		KELCH repeat	529..572	CDD:276965
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000