Protein Alignment Myc and MYC

DIOPT Version :9

• Sequence 1: NP_001259204.1
• Gene: Myc / 31310
• FlyBaseID: FBgn0262656
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 81/260 - (31%)
• Similarity: 114/260 - (43%)
• Gaps: 38/260 - (14%)

  Fly   460 PYTPASSSPVKSVA--NSRYPSPSSTPYQNCSSASPSYSPLSV---DSSNVSSSSSSSSSQSSFT 519
            ||....||..||.|  :|...||||....:.:.:||..||..:   :.:..::||.|...|....
Human   211 PYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEE 275

  Fly   520 TSSSNKGRKRSSLKDPGLLISSSSVYLPGVNNKVTHSSMMSKKSRGKKVVGTSSGN-TSPISSGQ 583
            ........||.:   ||....|.|....| ::|..||.::.|:..    |.|...| .:|.|:.:
Human   276 EIDVVSVEKRQA---PGKRSESGSPSAGG-HSKPPHSPLVLKRCH----VSTHQHNYAAPPSTRK 332

  Fly   584 DVDAMDR------NWQRRSGGIATSTSSNSSVHRKDFVLGFDEADTIE--KRNQHNDMERQRRIG 640
            |..|..|      ...|:.......||..||             ||.|  ||..||.:|||||..
Human   333 DYPAAKRVKLDSVRVLRQISNNRKCTSPRSS-------------DTEENVKRRTHNVLERQRRNE 384

  Fly   641 LKNLFEALKKQIPTIRDKERAPKVNILREAAKLCIQLTQEEKELSMQRQLLSL---QLKQRQDTL 702
            ||..|.||:.|||.:.:.|:||||.||::|....:.:..||::|..:..||..   |||.:.:.|
Human   385 LKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQL 449

  Fly   703  702
            Human   450  449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myc	NP_001259204.1	HLH	625..682	CDD:238036	27/58 (47%)
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	41/156 (26%)
		HLH	370..426	CDD:238036	26/55 (47%)
		Myc-LZ	423..453	CDD:280500	9/27 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1.056642	Normalized mean entropy	S7029
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto90556
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45851
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4673
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.990