Protein Alignment Myc and MNT

DIOPT Version :10

• Sequence 1: NP_525062.2
• Gene: Myc / 31310
• FlyBaseID: FBgn0262656
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_011522170.1
• Gene: MNT / 4335
• HGNCID: 7188
• Length: 590
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 78/370 - (21%)
• Similarity: 133/370 - (35%)
• Gaps: 98/370 - (26%)

  Fly   373 KNNSNGMLHMMHITDHSYTRCNDMVDDGPNLETPSDSDEEIDVVSYTDKKLPTNPSCHLMGALQF 437
            ::.:.|...:.|:...| |||:....:...||...:.::         ||  .|....|
Human    11 EDRAQGSERLSHLLPPS-TRCSSKEQERLRLEQEREQEQ---------KK--ANSLARL------ 57

  Fly   438 QMAHKISIDHMKQKPRYNNFNLPYTPASSS----------------PVKSVANSRYPSPSSTPYQ 486
              ||.:.:    ::||.....||.:|.:..                |:..|.||..|.|...|..
Human    58 --AHTLPV----EEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLP 116

  Fly   487 NCSSASP--SYSPLSVDSSNVSSSSSS---SSSQ----------SSFTTSSSNKGRKRSSLKDPG 536
            ..:...|  ...|..|.:..:|....:   |..|          |..|...:...:....|..|.
Human   117 AAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPV 181

  Fly   537 LLISSSSVYLPGVNNKVTHSSMMSKKSRGKKVVGTSSGNTSPISSGQDVDAMDRNWQRRSGGIAT 601
            |.|:..    |||      ...::.:......:||..     ::..::|.:.::  ::|.|||.|
Human   182 LTIAPH----PGV------QPQLAPQQPPPPTLGTLK-----LAPAEEVKSSEQ--KKRPGGIGT 229

  Fly   602 STSSNSSVHRKDFVLGFDEADTIEKRNQHNDMERQRRIGLKNLFEALKKQIPTIRDKERAPKVNI 666
                                     |..||.:|:.||..||..||.||:.||.:.|| :...:::
Human   230 -------------------------REVHNKLEKNRRAHLKECFETLKRNIPNVDDK-KTSNLSV 268

  Fly   667 LREAAKLCIQLTQEEKELSMQRQLLSLQLKQRQDTLASYQMELNE 711
            ||.|.:....|.::|||...:.:.|:.:....|..||..:.||::
Human   269 LRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQ 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myc	NP_525062.2	bHLHzip_Myc	626..702	CDD:381406	25/75 (33%)
MNT	XP_011522170.1	bHLHzip_Mnt	228..304	CDD:381408	26/101 (26%)
		CALCOCO1	<262..380	CDD:462303	13/52 (25%)