Protein Alignment HLF and CG7786

DIOPT Version :10

• Sequence 1: XP_005257326.1
• Gene: HLF / 3131
• HGNCID: 4977
• Length: 296
• Species: Homo sapiens
• Sequence 2: NP_611101.1
• Gene: CG7786 / 36802
• FlyBaseID: FBgn0034096
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 195
• Identity: 56/195 - (28%)
• Similarity: 86/195 - (44%)
• Gaps: 36/195 - (18%)

Human   109 HPPGLQPASSAAPSV---MDLSSRASAPLHP-------------GIPSPNCMQSPIRPGQLLPAN 157
            |.|...|......:|   .:|.:...:..:|             |:..|. |....|..:.|||.
  Fly     2 HSPAQSPILDVTETVSMHSELDAELESKNNPSYSISIPQNLRLTGLGFPG-MIGAKRSSETLPAF 65

Human   158 RNTPSPIDP-DTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPD 221
            .....|... ..::.|:      .:|....:.|..||.....:....|.:|.|
  Fly    66 EYIAPPSHALQALEFPL------MELNRVGVIGGGMFPGFVHRRVRGEKRPIP------------ 112

Human   222 DLKQDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNIL 286
            :.::|.||:.||::||.|||||||||:::|::||.||:.||:|||.||.:|..||.||...:.:|
  Fly   113 EAQKDAKYFERRKRNNEAAKRSRDARKIREDRIAFRAALLEQENSILRAQVLALRDELQTVRQLL 177

Human   287  286
              Fly   178  177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLF	XP_005257326.1	bZIP_HLF	226..284	CDD:269843	33/57 (58%)
		coiled coil	226..284	CDD:269843	33/57 (58%)
CG7786	NP_611101.1	bZIP_HLF	116..175	CDD:269843	33/58 (57%)
		coiled coil	117..175	CDD:269843	33/57 (58%)