Protein Alignment dnc and pde4b

DIOPT Version :9

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: XP_031756141.1
• Gene: pde4b / 780324
• XenbaseID: XB-GENE-963512
• Length: 733
• Species: Xenopus tropicalis
• Alignment Length: 769
• Identity: 410/769 - (53%)
• Similarity: 517/769 - (67%)
• Gaps: 92/769 - (11%)

  Fly   458 QNSSSVSVAAHHRLTSSSASALATSHPSNSQLLPTSKMQAEQGSIGDLQ--KYHSRYLK------ 514
            ::.|.::|.|...:.:.:...|:.|:.|....:.....:.::...|.||  ..|.|.::
 Frog     3 KSRSVMTVTAEDNVQNFTEVCLSKSYSSYGYNMGIDLWKGKRFCSGTLQLPPLHHRQMRRAKTPD 67

  Fly   515 --NRRHTLANV-------------RFDVENG-QGARSPLE-GGSPSAGLVLQ----NLPQRRESF 558
              :|..||..:             .|||||| ...||||: ..||.:||||.    :..||||||
 Frog    68 YIHRPTTLPLLLPPKIAVTPVEKDSFDVENGPTPGRSPLDHQASPGSGLVLHTNFTSHNQRRESF 132

  Fly   559 LYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSL 623
            |||||||:::|||:||||||.|||:             ||:|||||||||:||||||||||...|
 Frog   133 LYRSDSDYDLSPKTMSRNSSAASEQ-------------HGDDLIVTPFAQVLASLRSVRNNFTVL 184

  Fly   624 TNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSD 688
            |||..:...|.|       .:..|..:.::..|::|.::|.||:|||||||||||||||:||||:
 Frog   185 TNVHGAPNKRSP-------MTTQPQISRVNLQEDSYQKIAMDTLEELDWCLDQLETIQTYRSVSE 242

  Fly   689 MASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQ 753
            |||.|||||||:||:|.||.||||||:||||.|||||||.:.::||...:|
 Frog   243 MASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNDVEIPSPTQKD-------------- 293

  Fly   754 SAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDTWGIQIF 818
                  |.:..:...|:||||||: |.|::|.....:..|||:|..|:.|...|.:|:.||:.||
 Frog   294 ------REKKKKQQLMTQISGVKK-LMHSSSLNNTSMSRFGVKTEYEDMLSKELEDLNKWGLNIF 351

  Fly   819 SIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQST 883
            .:..:|.||||||:.|.|||.|:||.:..||..|.:.:..||||||..|..:|||||||||||||
 Frog   352 KVASYSCNRPLTCIMYAIFQERDLLKTFKIPADTLITYTMTLEDHYHSDVAYHNSLHAADVTQST 416

  Fly   884 NVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVA 948
            :|||:||||:.|||.||:..|:|||.||||||||::||||:|::||||||||||||||||||||.
 Frog   417 HVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG 481

  Fly   949 FKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDN 1013
            |||||.:.||||.|:.|||||:|||||||:||:||||||||||||||||||||||..||||||||
 Frog   482 FKLLQEEHCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDN 546

  Fly  1014 YTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEK 1078
            ||||||||.|:|||||||||||.|.||::|...:|||||.|||||||.||:||||||:|.|::||
 Frog   547 YTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEK 611

  Fly  1079 SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQE-----DR 1138
            |||||||||||||||||||||.|||||||||||:||::||||||.||.|. :||:.::     ::
 Frog   612 SQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPL-LDEHDKDCQGLSEK 675

  Fly  1139 IRFQVTLEESDQE----------------NLAELEEGDESGGESTTTGTTGTTA 1176
            ..|::||||.|.:                .|..:::|.|...::.|...|..|:
 Frog   676 FHFELTLEEEDSDGHDKDGDCLSFYSSTKTLHIVDQGMEDSPDADTEFLTDDTS 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDEase_I	870..1111	CDD:278654	194/240 (81%)
pde4b	XP_031756141.1	PDE4_UCR	164..279	CDD:407935	75/121 (62%)
		PDEase_I	403..644	CDD:395177	194/240 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	414	1.000	Domainoid score	I665
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	763	1.000	Inparanoid score	I546
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	1	1.000	-	-		FOG0000302
OrthoInspector	1	1.000	-	-		otm47870
Panther	1	1.100	-	-	LDO	PTHR11347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X171
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070