Protein Alignment dnc and pde9ab

DIOPT Version :10

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: XP_700447.6
• Gene: pde9ab / 571737
• ZFINID: ZDB-GENE-210629-1
• Length: 518
• Species: Danio rerio
• Alignment Length: 574
• Identity: 142/574 - (24%)
• Similarity: 252/574 - (43%)
• Gaps: 135/574 - (23%)

  Fly   565 DFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPAS 629
            |...|..:::||:::           :|:| |.|..:.:.|     ....:..|||..:
Zfish    37 DLLCSSSNIARNTAV-----------LLID-SEGALISIDP-----TMPANTPNNLYKV------ 78

  Fly   630 NKSRRPNQSSSASRSGNPPGAPLSQGEEAYTR------LATDTIEELDWC-----LDQLETIQTH 683
                .|:.::......:.....|||..|.:||      |.|:....|...     |:.|:.::..
Zfish    79 ----MPHSTNQGEEKEDMFQNVLSQVAEQFTRAFRNSELKTEVTNRLAMLEKRVELEGLKVVEIE 139

  Fly   684 RSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICS-TFLDKQQEFDLPSLRVEDNPELVAAN 747
            :..:|:..||             :...||:......|. .|.|..::.. |...|.:.|
Zfish   140 KCKNDLKKLK-------------DEMTSGSMRVNCNCKYNFTDDGKKLS-PRRDVPNYP------ 184

  Fly   748 AAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDT 812
                     :|..|:       ..|..:|:             |||                 |.
Zfish   185 ---------KYTLSQ-------ETIDALKK-------------PTF-----------------DV 203

  Fly   813 WGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAA 877
            |        .:..|..|:|:.| ::....|:....:.|.|...::..::::| :||||||..|..
Zfish   204 W--------HWEHNEMLSCLEY-MYHDLGLVKEFNMNPITLKRWLLAIQENY-RDNPFHNFRHCF 258

  Fly   878 DVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLEN 942
            .|:|....:::...|:...|..::...:.||..||:||||..|.:.:|:.:|||:.|||.|.|||
Zfish   259 CVSQMMYGMIHLCGLQDRLTMTDMCILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLEN 323

  Fly   943 HHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSG 1007
            ||.||||::|....|:||.|::.:..:.:|:.:|.::|:|||:||..:|...|..|
Zfish   324 HHCAVAFQILSMPECNIFANIEPESFKQIRQAIITLILATDMAKHGEILDSFKQKV--------- 379

  Fly  1008 VLLLDNY----TDRIQVLEN-LVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISP 1067
                ||:    .:.::.|:. |:.|.|:||..:|..:.:.||..|:||:|:|.|:|:..|:.::|
Zfish   380 ----DNFDCTNEEHVKSLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAP 440

  Fly  1068 MCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDIL-DTLEENRDYYQSM 1120
            ..||...|...:|:|||.:::.|::||...| .|..::|: ..|.::||:|:.:
Zfish   441 FMDRDKVTKPTAQIGFIKFVLIPMFETVMKL-FPQIEEIMVQPLRDSRDHYEEL 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDE4_UCR	603..725	CDD:465648	23/133 (17%)
		PDEase_I	870..1110	CDD:459723	83/245 (34%)
pde9ab	XP_700447.6	None