Protein Alignment dnc and pde4ba

DIOPT Version :10

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: XP_073810362.1
• Gene: pde4ba / 565706
• ZFINID: ZDB-GENE-030131-9570
• Length: 806
• Species: Danio rerio
• Alignment Length: 777
• Identity: 426/777 - (54%)
• Similarity: 517/777 - (66%)
• Gaps: 119/777 - (15%)

  Fly   465 VAAHHRLTS----SSASALATSHPSNSQLLPTSKMQAEQGSIG-----DLQKYHSRYLKN----- 515
            |....|.||    .|.|.|..|...:|:..|.|::.....|.|     ||::...|:..|
Zfish    62 VQDRERKTSQKMRKSRSVLTVSPNEDSKEPPDSRLSESFTSSGCTLGVDLRRRRRRFSGNLQLPP 126

  Fly   516 ------------------RRHTLANVR-------------FDVENGQGAR-SPLE-GGSPSAGLV 547
                              |..||..:.             ||||||..|. |||: ..||.:|||
Zfish   127 LSWRQMERSRSPDDEFMARPTTLPFITPPRIDITPVDTECFDVENGPSASCSPLDPQASPGSGLV 191

  Fly   548 LQ-NLP---QRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQ 608
            |. |.|   |||||||||||||:::||||||||||:|||             .||:|||||||||
Zfish   192 LHTNFPGHNQRRESFLYRSDSDYDLSPKSMSRNSSVASE-------------LHGDDLIVTPFAQ 243

  Fly   609 ILASLRSVRNNLLSLTNVPASNKSRRP-NQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDW 672
            :||||||||||...||||..::..|.| :...|.:|...|        :|:|.:||.:|:|||||
Zfish   244 VLASLRSVRNNFTVLTNVQCTSNKRSPVSNQPSITRVCLP--------DESYQKLAVETMEELDW 300

  Fly   673 CLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLPSLRV 737
            ||||||||||:||||||||.|||||||:||:|.||.||||||:||:|.:||||||.:.::||
Zfish   301 CLDQLETIQTYRSVSDMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVEIPS--- 362

  Fly   738 EDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFT-GERLPTFGVETPREN 801
             ..|:                ||.:..:...|:||||||: :||..|.. |  :..|||:|.:|:
Zfish   363 -PTPK----------------AREKKKKQQLMTQISGVKK-VSHGPSLNCG--IARFGVKTDKED 407

  Fly   802 ELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVK 866
            .|...|.:|:.||:.||::.|:|.||||||:.|.|||.|:||.:..||..||:.:|.||||||.:
Zfish   408 LLSKELEDLNRWGLNIFTVSEYSNNRPLTCIMYAIFQERDLLKTFKIPTDTFVTYMMTLEDHYHQ 472

  Fly   867 DNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELA 931
            |..:|||||||||.|||::||:||||:.|||.||:..|:|||.||||||||::||||:|::||||
Zfish   473 DVAYHNSLHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELA 537

  Fly   932 LMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKT 996
            ||||||||||||||||.|||||...||||.|:.||||.:||:||||:||:|||||||||||||||
Zfish   538 LMYNDESVLENHHLAVGFKLLQEDNCDIFQNLTKKQRTSLRRMVIDMVLATDMSKHMSLLADLKT 602

  Fly   997 MVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERES 1061
            |||||||..||||||||||||||||.|:|||||||||||.|.||::|...:|||||.|||:|||.
Zfish   603 MVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFHQGDRERER 667

  Fly  1062 GMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPP 1126
            ||:||||||:|.|::|||||||||||||||||||||||||||||||||||:||::||||||.||.
Zfish   668 GMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRNWYQSMIPQSPS 732

  Fly  1127 P---------SGVDENPQEDRIRFQVTLEESDQENLA--------ELEEGDESGG---ESTT 1168
            |         :|....|  |:.:|::||||.|.|...        |.||.:|..|   ||||
Zfish   733 PPFYQPDKEGNGGSSGP--DKFQFELTLEEEDSEGTEKDEQSQGDEEEEAEEDRGEEMESTT 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDE4_UCR	603..725	CDD:465648	76/122 (62%)
		PDEase_I	870..1110	CDD:459723	189/239 (79%)
pde4ba	XP_073810362.1	None