Protein Alignment dnc and pde9ac

DIOPT Version :10

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: XP_692819.5
• Gene: pde9ac / 564389
• ZFINID: ZDB-GENE-130530-807
• Length: 558
• Species: Danio rerio
• Alignment Length: 554
• Identity: 141/554 - (25%)
• Similarity: 249/554 - (44%)
• Gaps: 137/554 - (24%)

  Fly   608 QILASLRSV-RNNLLSLTN-----------VPASNKSRRPN-----QSSSASRSGNPPGA---PL 652
            ::|.|..:: ||..:.:|:           :|.:|    ||     ...|||:.|.....   .|
Zfish    76 ELLCSSSNIPRNTAIMMTDPEGAIVSIDPTMPTNN----PNFLYKIIPLSASQLGEKEDMFQNVL 136

  Fly   653 SQGEEAYTR------LATDTIEELDWC-----LDQLETIQTHRSVSDMASLKFKRMLNKELSHFS 706
            ||..|.::|      |.|:....|...     |:.|:.::..:..:||      |.|..|:
Zfish   137 SQVAEQFSRAFRINELKTEVTNRLAMLEKRVELEGLKVVEIEKCKNDM------RKLRDEM---- 191

  Fly   707 ESSRSGNQISEYICSTFLDKQQEF----DLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGP 767
             :||:|.:::......|.|..::.    |:||.                    .:|..|:
Zfish   192 -TSRAGARVNCPCKYNFSDDGKKLTPRRDIPSY--------------------PKYTLSQ----- 230

  Fly   768 PMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCV 832
              ..|..:|:             |||                 |.|        .:..|..|:|:
Zfish   231 --ETIEALKK-------------PTF-----------------DVW--------HWEHNEMLSCL 255

  Fly   833 AYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFT 897
            .| ::....|:....|.|.|...::..::::| :.|||||..|...|:|....:::...|:...|
Zfish   256 EY-MYHDLGLVKEFNINPITLKRWLLGIQENY-RSNPFHNFRHCFCVSQMMYGMIHLCNLQEKLT 318

  Fly   898 PLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCN 962
            ..::|..:.||..||:||||..|.:.:|:.:|||:.|||.|.|||||.||||::|....|:||.|
Zfish   319 LTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFAN 383

  Fly   963 MQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNY----TDRIQVLEN 1023
            ::.:..:.:|:.:|.::|:|||::|..:|...|..|             |::    .:.:..|:.
Zfish   384 VEPEAFKQIRQAIITLILATDMARHGEILDSFKHKV-------------DHFDFTNEEHVACLKM 435

  Fly  1024 -LVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYI 1087
             |:.|.|:||..:|..:.:.||..|:||:|:|.|:|:..|:.::...||...|...:|:|||.::
Zfish   436 VLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAAFMDREKVTKPTAQIGFIKFV 500

  Fly  1088 VHPLWETWADLVHPDAQDIL-DTLEENRDYYQSM 1120
            :.|::||...| .|..::|: ..|.::||:|:.:
Zfish   501 LIPMFETVMKL-FPQIEEIMVQPLRDSRDHYEEL 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDE4_UCR	603..725	CDD:465648	32/147 (22%)
		PDEase_I	870..1110	CDD:459723	81/245 (33%)
pde9ac	XP_692819.5	None