Protein Alignment dnc and pde10a

DIOPT Version :9

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: XP_017214212.1
• Gene: pde10a / 394077
• ZFINID: ZDB-GENE-040426-1115
• Length: 852
• Species: Danio rerio
• Alignment Length: 745
• Identity: 154/745 - (20%)
• Similarity: 275/745 - (36%)
• Gaps: 209/745 - (28%)

  Fly   532 GARSPLEGGSPSAGL-----VLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASI 591
            ||:..|.|..||..:     :..::.:.|::.|.......|..|....::|.|
Zfish   198 GAKEGLPGLIPSGPITFGTTIAAHVAKTRKTLLVEDIMGDERFPHGTGQDSGI------------ 250

  Fly   592 LVDRSHGEDL--IVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQ 654
               |.|....  |:|....::|.|...|            :..|.|..              ||.
Zfish   251 ---RVHSVLCLPILTAIGDLIAILELHR------------HLGREPFN--------------LSH 286

  Fly   655 GEEAYTRL--ATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRM--LNKELSHFSESSRSGNQI 715
            .|.|...|  |:..|.::..|....:..:.:..:.|::...|..:  ::..|.|....::  |.:
Zfish   287 QEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAK--NLV 349

  Fly   716 SEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQ--YARSRSPRGPPMSQISG-VKR 777
            :...|:.|     :.|      .:|.||.:.....|:::.|:  :.:::..|......|:| |.|
Zfish   350 NADRCALF-----QVD------HNNKELYSDLFDIGEENEGKPVFRKTKEIRFSIEKGIAGQVAR 403

  Fly   778 PLSHTNSFTGERL--------PTFGVETPRENEL-----------------GTLLG--------- 808
                    |||.|        |.|.    ||.:|                 ||::|
Zfish   404 --------TGEVLNIPDAYADPRFN----REVDLYTGYTTRNILCMPIVSRGTVIGVVQMVNKLG 456

  Fly   809 -----ELDTWGIQIFSI---------GEFSVNRPLTCV---------AYTIFQSRE--LLTSLMI 848
                 :.|....::|::         ..:...|...|:         .::|..|.|  .||.|.:
Zfish   457 GSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTL 521

  Fly   849 P---------------------PKTFL------------------NFMSTLEDHYVKDNPFHNSL 874
            |                     |..|:                  .|..::..:| :..|:||..
Zfish   522 PSAIYKEIELFHFDIAPFEELWPAIFVYMVHNSCGKTSFELEKLCRFTMSVRKNY-RRVPYHNWK 585

  Fly   875 HAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESV 939
            ||..|......:|....  |:||.||..|.|.|...||:||.|.:|.:|......||.:|: .|.
Zfish   586 HAVTVAHCMYAILQKTT--GIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYS-TST 647

  Fly   940 LENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVA 1004
            :|.||.:....:||.:|.:||.|:...:.:.:.:::...:::||::.:......|..::.|
Zfish   648 MEQHHFSQTVSILQLEGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLST---- 708

  Fly  1005 GSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMC 1069
              |.|.|:|...|.:|:..::...||.:.||..|:.:.....:..||:.:||:.::.||....|.
Zfish   709 --GALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMM 771

  Fly  1070 DRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPPPSGVDEN 1133
            ||... .:.:.||||.:.:..|.:.|.::| .|.:..:|:...||...::.::      .|.|
Zfish   772 DRDKKDEVPQGQVGFYNAVAIPCYTTLSEL-FPPSVPLLEACRENLSQWERIV------QGED-- 827

  Fly  1134 PQEDRIRFQVTLEESDQENLAELEEGDESG 1163
                     |:...|.:|  ||:.|..:||
Zfish   828 ---------VSAWSSTEE--AEVSETSDSG 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDEase_I	870..1111	CDD:278654	67/241 (28%)
pde10a	XP_017214212.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920