Protein Alignment dnc and Pde1c

DIOPT Version :9

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: NP_001137817.1
• Gene: Pde1c / 34594
• FlyBaseID: FBgn0264815
• Length: 1173
• Species: Drosophila melanogaster
• Alignment Length: 1241
• Identity: 286/1241 - (23%)
• Similarity: 428/1241 - (34%)
• Gaps: 424/1241 - (34%)

  Fly    52 ATGGVGGGGG-------SGSGGGGCGSGSGSGSGKRKSKARTKCFGGTVFRCCLPCRGGGSAAPA 109
            |:||.|..||       |.|.|||..||:.|||....|...|               |.|||:..
  Fly   168 ASGGPGSSGGTSGAATSSSSSGGGAASGAASGSVGPASGTAT---------------GTGSASGG 217

  Fly   110 TSPPQTPAQTPDELKVIPEDCNLEKSAEQKRDLLERNNKEDDLLNRTVSGSELDLYGGAGGGTKK 174
            .....||||                                :..:.||  |||     :|.|:..
  Fly   218 AGGVSTPAQ--------------------------------EAASPTV--SEL-----SGSGSNA 243

  Fly   175 HSLADTIDTSVTTPISLKTLINDVDE----ELDQQL-SAADIAAASLASGL----------VARR 224
                 ||:..|....|| |:|...:.    :.|.|| |.:..|.:|.|.|:          :|.|
  Fly   244 -----TINGQVARHGSL-TIIRRTNSRNFTQFDGQLASPSSTACSSTAPGIGFAQTPLSEPLAER 302

  Fly   225 AEPETLSDASVSPTAVVQQQQQQQQQLQQPLLQSQPHFVPSSGNI--------------LSQVTL 275
            ........::.|.:|...:...|......|...:.....|||.|.              |||..:
  Fly   303 LSFRASGGSNGSASAGDSRSSNQGPSNSGPAASAAVKMQPSSPNATNYLADNIQISSANLSQTEM 367

  Fly   276 YSGSNPSTNPCQSAVQ-------NQGQNSNPNPNQNPNTNPNQNQQRCSCQPQTSPLPHIKEEEE 333
            ..|.:.:......::.       .:|....|..:.:....|: |....:.|..|..||.:...:.
  Fly   368 VVGRDSADYTAMHSINVGVGNSFLRGDTDIPQESGHSFETPS-NMSFTAGQWDTESLPPVDTPDA 431

  Fly   334 SDQANFKHQTSLK--EHQPLPPPITIA------------------------TGYCGSCESVH--- 369
            .::|..:.::.|:  :|:      |:|                        .|..|:|::::
  Fly   432 LNKAAGRIRSLLRRMDHE------TVAYEDMQRNLHYAARVLEAVFIDESREGCNGNCKNLNCSR 490

  Fly   370 HS------------SATSSSAGTVPPGGQQTQEYIAGTSSTPSPRIKLKFRKPHKSCWSRIVLAP 422
            ||            |..|.|.....|||       ||...||
  Fly   491 HSHGRDDQQQDNNNSNRSCSLQEASPGG-------AGAGVTP----------------------- 525

  Fly   423 IGSAGGSSSATTVIGSNSNETLASSSTTGGTATTTQNSSSVSVAAHHRLTSSSASALATSHPSNS 487
                          |:::.:::  .|.|.|.:...|..|.                 .|..|||:
  Fly   526 --------------GADNQDSI--ESRTKGVSQAPQTHSG-----------------PTGPPSNT 557

  Fly   488 Q----LLPTSKMQAEQGSIGDLQKYHSRYLKNRRHTLANVRFDVENGQGARSPLEGGSPSAGLVL 548
            .    ..|..|:|.                     .|..||..|.....::.|.:.|.|
  Fly   558 SSETIAQPAPKLQP---------------------ALETVRESVMEESPSKDPGDKGPP------ 595

  Fly   549 QNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASL 613
                                .|.|.|                                     :|
  Fly   596 --------------------PPASTS-------------------------------------TL 603

  Fly   614 RSVRNNLLSLTNVPASNKSRRPNQSSSASRSG---NPPGAPLSQGEEAYTRLATDTIEELDWCLD 675
            .|......|.|..|::..:.  :|:.||..||   ||...      ....||.|.|     |.
  Fly   604 TSQTTTSSSATAEPSAKAAE--SQAGSAGSSGSCSNPAAV------HRQRRLRTPT-----WA-- 653

  Fly   676 QLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSG--NQISEYICSTF-----LDKQQEFDLP 733
                    ||:|..     |..|..|....||.....  .::.|::.|||     ..:::..:.|
  Fly   654 --------RSMSTN-----KTRLADEDDELSEVQPDAVPPEVREWLASTFTRQMATSRRKSDEKP 705

  Fly   734 SLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETP 798
            ..|      .||....||......|.|..|                        ..|..|..:..
  Fly   706 KFR------SVAHAIRAGIFVDRMYRRVSS------------------------SALTAFPPDVV 740

  Fly   799 RENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDH 863
            |      ||..||.|...:|::.|.:..:.:..|||.:|.....:....|.|.....|:..:|:.
  Fly   741 R------LLKNLDDWTFDVFALTEAASGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEG 799

  Fly   864 YVK-DNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSS 927
            |.: .||:||:|||.||.|:.:..|....|....|.||:..:|.||.:||.:|.|.||.|.|.|.
  Fly   800 YCRYRNPYHNNLHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSG 864

  Fly   928 SELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKH---MS 989
            ||.||:|||.:||||||.:.:|:||:....:|..::.:::.:.||.:||::||.|||:.|   |.
  Fly   865 SETALLYNDRAVLENHHASASFRLLREDEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMK 929

  Fly   990 LLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQ 1054
            .:..|.|:.|..             .|:.:||..::||.|:|:|.|...::.||..||:||||.|
  Fly   930 AMRQLLTLQEAT-------------IDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQ 981

  Fly  1055 GDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADL-------VHPDAQDILDTLEE 1112
            ||.|:|.|:..||:|||:|..:.:||:.|||:||.|.....:|:       :.|..:....||.|
  Fly   982 GDLEKELGLPFSPLCDRNNTLVAESQICFIDFIVEPSMGVMSDMLELILAPIAPMNKSKPATLVE 1046

  Fly  1113 NRDYYQS------MIPPSPPPSGVDENPQEDRIRFQVTLEESDQENLAELEEGDESGGESTTTGT 1171
            :.....|      :||.|.....:|: |::.|...:.|..|.    ||.             ...
  Fly  1047 HETTANSTTNSAIVIPNSGITPSMDK-PRDHRTEAKTTAAEC----LAR-------------KSV 1093

  Fly  1172 TGTTAA 1177
            |||||:
  Fly  1094 TGTTAS 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDEase_I	870..1111	CDD:278654	96/250 (38%)
Pde1c	NP_001137817.1	PDEase_I_N	666..722	CDD:285672	13/61 (21%)
		PDEase_I	807..1026	CDD:278654	94/231 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I1950
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439875at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46491
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X171
	6	6.020