Protein Alignment dnc and Pde4c

DIOPT Version :9

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: NP_001263694.1
• Gene: Pde4c / 290646
• RGDID: 727918
• Length: 671
• Species: Rattus norvegicus
• Alignment Length: 698
• Identity: 380/698 - (54%)
• Similarity: 478/698 - (68%)
• Gaps: 89/698 - (12%)

  Fly   485 SNSQLLPTSKMQAEQGSIGDLQK-------YHSRYLKNRRHTLANVRFDVENG-QGARSPLEGGS 541
            |.:.|||  .:.:..||.|:.:.       ..||..: |.|..|...||:||| ...|.||:..|
  Rat    40 SGTLLLP--PLSSRLGSSGEAESAAPVVFTIGSRGTE-RSHGSAQSSFDLENGLPSGRGPLDAQS 101

  Fly   542 PSA-GLVLQ---NLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLI 602
            .|: |..||   :..|||||||||||||.|.|||::||.||.||:             .||||:|
  Rat   102 GSSLGRALQPPVHHGQRRESFLYRSDSDHEPSPKAVSRTSSAASD-------------LHGEDMI 153

  Fly   603 VTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRS---GNPP-----GAPLSQGEEAY 659
            ||||||:|||||:||:|:.:|.           :.:.||:|.   |.||     .||   .||:.
  Rat   154 VTPFAQVLASLRTVRSNVAALA-----------HGAGSATRQALLGTPPQSSQQAAP---AEESG 204

  Fly   660 TRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFL 724
            .:||.:|:|||||||:||||:||.|||.:|||.|||||||:||:|.||:||||||:||||..|||
  Rat   205 LQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFL 269

  Fly   725 DKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGER 789
            |:|.|.:||:...||:|.                         ||:||:|:::. .|| |.....
  Rat   270 DQQAEVELPAPPTEDHPW-------------------------PMAQITGLRKS-CHT-SLPTAA 307

  Fly   790 LPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFL 854
            :|.|||:|.:|.:|...|.:.:.||..:|.:.|.|.|||||.|.:::.|.|:||.:..||..|.|
  Rat   308 IPRFGVQTDQEEQLAKELEDTNKWGFDVFKVAELSGNRPLTAVIFSVLQERDLLKTFQIPADTLL 372

  Fly   855 NFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLT 919
            .::.|||.||..:..:|||:|||||.||.:|||.|||||.|||.|||..|:||..||||||||::
  Rat   373 RYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVS 437

  Fly   920 NQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDM 984
            ||||:|::|||||||||.||||||||||.|||||.:.||||.|:..||:.:||:||||:||:|||
  Rat   438 NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDM 502

  Fly   985 SKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLME 1049
            |||||||||||||||||||...||||||||:||||||::||||||||||.||||||::|...:|.
  Rat   503 SKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMA 567

  Fly  1050 EFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENR 1114
            |||.|||:|||||:|||||||:|.|::|||||||||||.||||||||||||||||::|||||:||
  Rat   568 EFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNR 632

  Fly  1115 DYYQSMIPPSPPPS-GVDENPQEDRIRFQVTLEESDQENLAELEEGDE 1161
            ::|||.:|.|||.: |      .||.:|::||||:::|     ||.||
  Rat   633 EWYQSRVPCSPPHAIG------PDRFKFELTLEETEEE-----EEEDE 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDEase_I	870..1111	CDD:278654	183/240 (76%)
Pde4c	NP_001263694.1	PDEase_I	388..629	CDD:278654	183/240 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	408	1.000	Domainoid score	I676
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	1	1.000	-	-		FOG0000302
OrthoInspector	1	1.000	-	-		otm44825
orthoMCL	1	0.900	-	-		OOG6_100782
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X171
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.680