Protein Alignment dnc and Pde7a

DIOPT Version :9

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: NP_001116231.1
• Gene: Pde7a / 18583
• MGIID: 1202402
• Length: 482
• Species: Mus musculus
• Alignment Length: 535
• Identity: 144/535 - (26%)
• Similarity: 237/535 - (44%)
• Gaps: 79/535 - (14%)

  Fly   626 VPASNKSRRP--NQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSD 688
            ||....|||.  :.|||::..|.|....|||...|   ::.|:                    ||
Mouse    16 VPQHVLSRRGAISFSSSSALFGCPHPRQLSQRRGA---ISYDS--------------------SD 57

  Fly   689 MASLKFKRMLN----KELSHFSESSRSGNQISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAA 749
            ..:| :.|||.    :..:.| |:.|.|:.  .||.......|.:.:..          |:|...
Mouse    58 QTAL-YIRMLGDVRVRSRAGF-ETERRGSH--PYIDFRIFHSQSDIEAS----------VSARNI 108

  Fly   750 AGQQSAGQYAR-SRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDTW 813
            ....|..:|.| ||..||..:.....:                   ::.....:...:|.::..|
Mouse   109 RRLLSFQRYLRSSRVFRGATVCSSLDI-------------------LDEDYNGQAKCMLEKVGNW 154

  Fly   814 GIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAAD 878
            ...||.....:....|..:.:.:|....|:....:.......|:..:::.|...||:||::||||
Mouse   155 NFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAAD 219

  Fly   879 VTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENH 943
            |||:.:..|..|.|....||.::..:|.||..||:||||:...||:.::..||.:|.:.||||||
Mouse   220 VTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENH 284

  Fly   944 HLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGV 1008
            |...|..||:..|  :|.::..:.||.:...:..::|:||:|:....|:..::.::      .|.
Mouse   285 HWRSAVGLLRESG--LFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLD------KGD 341

  Fly  1009 LLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHN 1073
            |.||:...|..||:..:.|||:.||.:...|.|:|...:.||||.|||.|::..:.:||:|||..
Mouse   342 LHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQT 406

  Fly  1074 ATIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEENRDYYQSMIPPSPPPSGVDENPQED 1137
            .:|...|:||:.|:|.||:..||...... :|.:|..:..|:..::.:  ....||..|.|
Mouse   407 ESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGL--QRQQPSSEDAN---- 465

  Fly  1138 RIRFQVTLEESDQEN 1152
             ..|::..:...|||
Mouse   466 -AAFELNSQLLTQEN 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDEase_I	870..1111	CDD:278654	87/241 (36%)
Pde7a	NP_001116231.1	Endonuc-BglII	<51..128	CDD:286304	23/110 (21%)
		PDEase_I	211..431	CDD:278654	85/227 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820