Protein Alignment dnc and Pde7b

DIOPT Version :10

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: XP_008756813.1
• Gene: Pde7b / 140929
• RGDID: 621016
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 370
• Identity: 112/370 - (30%)
• Similarity: 188/370 - (50%)
• Gaps: 18/370 - (4%)

  Fly   775 VKRPLSHTNSFTGERL-----PTFGVETPRENELGT---LLGELDTWGIQIFSIGEFSVNRPLTC 831
            |:|.||....|...||     |...:....|:.||.   :|.::..|...||.....:....|..
  Rat   121 VRRLLSFQRHFHESRLLRGMTPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVT 185

  Fly   832 VAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVF 896
            :...:|.|..|:....:...|...|:..:::.|...||:||::|||||||:.:..|..|.|....
  Rat   186 LLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFL 250

  Fly   897 TPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFC 961
            |||::...|.||..|||||||:...||:.::..||.:|.:.|||||||......:|:..  .:..
  Rat   251 TPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRES--RLLA 313

  Fly   962 NMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVH 1026
            ::.|:..|.:.:.:..::|:||:::....|..||..:..|.      |.|:|..||..:|:..:.
  Rat   314 HLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKD------LRLENIQDRHFMLQIALK 372

  Fly  1027 CADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPL 1091
            |||:.||.:...:.|:|...:.|||:.|||.|::..::|||:|::...:|...|:||:.|||.||
  Rat   373 CADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPL 437

  Fly  1092 WETWADLVHPD--AQDILDTLEENRDYYQSMIPPSPPPSGVDENP 1134
            :..||......  ::.:|:.|..|:..::|::.......|..::|
  Rat   438 FREWARFTGNSTLSESMLNHLAHNKAQWKSLLSNQHRRRGSGQDP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDE4_UCR	603..725	CDD:465648
		PDEase_I	870..1110	CDD:459723	83/241 (34%)
Pde7b	XP_008756813.1	PDEase_I	224..458	CDD:459723	83/241 (34%)