Protein Alignment dnc and Pde6c

DIOPT Version :9

• Sequence 1: NP_726846.1
• Gene: dnc / 31309
• FlyBaseID: FBgn0000479
• Length: 1209
• Species: Drosophila melanogaster
• Sequence 2: NP_291092.1
• Gene: Pde6c / 110855
• MGIID: 105956
• Length: 861
• Species: Mus musculus
• Alignment Length: 585
• Identity: 134/585 - (22%)
• Similarity: 230/585 - (39%)
• Gaps: 155/585 - (26%)

  Fly   616 VRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCL---DQL 677
            |..|:|||   |..||  :.:....|:......|.|..:.:|..|...|   :.|.|.|   |..
Mouse   383 VIKNVLSL---PIVNK--KEDIVGVATFYNRKDGKPFDEHDEHITETLT---QFLGWSLLNTDTY 439

  Fly   678 ETIQTHRSVSDMAS-----------------LKFKRMLNKELSHFSESSRSGNQISEYICSTFLD 725
            |.:....|..|:|.                 ||||..||.|:                     ::
Mouse   440 ERVNKLESRKDIAQEMVMNLTKATPDEISSILKFKEKLNVEV---------------------IE 483

  Fly   726 KQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERL 790
            :.:|..|.::..||.|:                     ||...:.:......|::.
Mouse   484 ECEERQLLAILKEDLPD---------------------PRTADLYEFCFSDFPITE--------- 518

  Fly   791 PTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLN 855
                             .||...|:::|    ..:|               ::....:|.:....
Mouse   519 -----------------HELVKCGLRLF----LEIN---------------VVEKFKVPVEVLTR 547

  Fly   856 FMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTN 920
            :|.|:...| :...:||..|..:|.|:...||.|..|:..:|.||....|.||..||:||.|..|
Mouse   548 WMYTVRKGY-RPVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNN 611

  Fly   921 QFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMS 985
            .:.:.|:|.||.::. .|:||.|||..:..|||::..:||.|:.|:|.:|:..:....:::||::
Mouse   612 LYQMKSTSPLARLHG-TSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLFEVAIIATDLA 675

  Fly   986 ----------KHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLY 1040
                      |.:.....:::..||.|...|      :.|.:..::..::...|||..|||..:.
Mouse   676 LYFKKRTMFQKIVDTCEQMQSEEETIKYVTS------DPTKKEVIMAMMMTACDLSAITKPWEVQ 734

  Fly  1041 KRWVALLMEEFFLQGDKERE-SGMDISPMCDRHNA-TIEKSQVGFIDYIVHPLWETWADLVHPDA 1103
            .:...|:..||:.|||.||. ......||.||... .:.|.||||||::...:::.::.. |.:.
Mouse   735 SQVALLVANEFWEQGDLERTVLQQQPIPMMDRSKKDELPKLQVGFIDFVCTFVYKEFSRF-HGEI 798

  Fly  1104 QDILDTLEENRDYYQSMIPPSPPPSGVDENPQEDRIRFQVTLEESDQENLAELEEGDESGGESTT 1168
            ..:|:.|:.||..::|:             .:|...:.:||.||:.:      :|.:.|.|::.|
Mouse   799 TPMLNGLQNNRVEWKSL-------------AEEYEAKVKVTEEEAGK------QEEEASDGKAAT 844

  Fly  1169  1168
            Mouse   845  844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnc	NP_726846.1	PDEase_I	870..1111	CDD:278654	75/252 (30%)
Pde6c	NP_291092.1	GAF	81..232	CDD:214500
		GAF	256..443	CDD:214500	19/67 (28%)
		PDEase_I	561..806	CDD:278654	75/252 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	826..861		7/25 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820