Protein Alignment CG10793 and PSMC5

DIOPT Version :10

• Sequence 1: NP_570054.2
• Gene: CG10793 / 31308
• FlyBaseID: FBgn0288967
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_002796.4
• Gene: PSMC5 / 5705
• HGNCID: 9552
• Length: 406
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 96/339 - (28%)
• Similarity: 167/339 - (49%)
• Gaps: 37/339 - (10%)

  Fly   135 VGAATQALSNEQPLQIKKMETATESNGQ-----DNACEIE------HVHLGGDDVLFSSLEWQSL 188
            ||...:|:..      ||:.......|:     |...:|.      .|.|..|......:....:
Human    73 VGEVVRAMDK------KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKV 131

  Fly   189 AELVKTSILQENIKIKWSDVCGNQRAIELIKEAVLTPIEFPQLF-AHGLKPWRSLLLHGPPGSGK 252
            ..||...::::.....:..:.|..:.|:.|||.:..|::.|:|| |.|:...:.:||:||||:||
Human   132 DPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGK 196

  Fly   253 TLLAKALYSETQGQVTFFNITASIMVSKWRGESEKILRVLFHMAAKRAPSVIFFDEIESLTSKR- 316
            ||||:|:...|  ..||..::.|.:|.|:.||..:::|.||.||.:.|||:||.|||:|:.|.|
Human   197 TLLARAVAHHT--DCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259

  Fly   317 DRATDHESS-KRFKNELLQLLDGMEHSLNGVFVLASTNLPWDIDEAFLR--RFEKKLLVQLPNAA 378
            :..:..:|. :|...|||..|||.|.:.| :.|:.:||....:|.|.||  |.::|:....||..
Human   260 EGGSGGDSEVQRTMLELLNQLDGFEATKN-IKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEE 323

  Fly   379 ERSCLI---NRLLGSSISLNPRLLEQLVEISDHFTGDEIRLACKEISMHRVRCATKIGDRSIGLL 440
            .|..::   :|.:..:..:|   |.::.|:....:|.|::..|.|..|:.:|      :|.:.:.
Human   324 ARLDILKIHSRKMNLTRGIN---LRKIAELMPGASGAEVKGVCTEAGMYALR------ERRVHVT 379

  Fly   441 AKESPAAIEANVEK 454
            .::...|:...::|
Human   380 QEDFEMAVAKVMQK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10793	NP_570054.2	LisH	31..55	CDD:462501
		RecA-like_VPS4-like	208..372	CDD:410917	67/168 (40%)
PSMC5	NP_002796.4	PRK03992	24..400	CDD:179699	96/339 (28%)
		May mediate interaction with PRPF9. /evidence=ECO:0000250|UniProtKB:P62196	186..406		72/220 (33%)