Protein Alignment CG10793 and spast

DIOPT Version :10

• Sequence 1: NP_570054.2
• Gene: CG10793 / 31308
• FlyBaseID: FBgn0288967
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: XP_012818464.1
• Gene: spast / 549207
• XenbaseID: XB-GENE-947839
• Length: 603
• Species: Xenopus tropicalis
• Alignment Length: 308
• Identity: 103/308 - (33%)
• Similarity: 168/308 - (54%)
• Gaps: 34/308 - (11%)

  Fly   187 SLAELVKTSILQENIKIKWSDVCGNQRAIELIKEAVLTPIEFPQLFAHGLK-PWRSLLLHGPPGS 250
            :||.|:...|:.....:|::|:.|...|.:.::|.|:.|...|:||. ||: |.|.|||.||||:
 Frog   310 NLANLILNEIVDSGPTVKFADIAGQDLAKQALQEIVILPSIRPELFT-GLRAPARGLLLFGPPGN 373

  Fly   251 GKTLLAKALYSETQGQVTFFNITASIMVSKWRGESEKILRVLFHMAAKRAPSVIFFDEIESLTSK 315
            |||:||||:.:|:  ..|||||:|:.:.||:.||.||::|.||.:|.:..||:||.||::||..:
 Frog   374 GKTMLAKAVAAES--NATFFNISAASLTSKYVGEGEKLVRALFSVARELQPSIIFIDEVDSLLCE 436

  Fly   316 RDRATDHESSKRFKNELLQLLDGMEHSLNG-VFVLASTNLPWDIDEAFLRRFEKKLLVQLPNAAE 379
            | |..:|::|:|.|.|.|...||::...:. |.|:.:||.|.::|:|.||||.|::.|.|||...
 Frog   437 R-REGEHDASRRLKTEFLIEFDGVQSGGDDRVLVMGATNRPQELDDAVLRRFTKRVYVSLPNEET 500

  Fly   380 RSCLINRLLGSSIS-LNPRLLEQLVEISDHFTGDEIRLACKEISMHRVRCATKIGDRSIGLLAKE 443
            |..|:..||....: ||.:.|.||..:::.::|.:|....|              |.::|.:.:.
 Frog   501 RLLLLKNLLSKQGNPLNEKELTQLSRLTEGYSGSDITALAK--------------DAALGPIREL 551

  Fly   444 SPAAIEANVEKAFRQVR-------------PLGQKLLAKHEQWQQENG 478
            .|..::.......|.::             .:....|..:.:|.:|.|
 Frog   552 KPEQVKNMAASEMRNIKYSDFLSSLKKIKCSVSPSTLESYIRWNKEFG 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10793	NP_570054.2	LisH	31..55	CDD:462501
		RecA-like_VPS4-like	208..372	CDD:410917	73/165 (44%)
spast	XP_012818464.1	MIT_spastin	110..188	CDD:239142
		RecA-like_spastin	330..493	CDD:410932	74/166 (45%)
		AAA_lid_3	520..554	CDD:465537	8/47 (17%)
		Vps4_C	<567..599	CDD:462762	3/31 (10%)