Protein Alignment Chd7 and kis

DIOPT Version :10

• Sequence 1: NP_001101376.2
• Gene: Chd7 / 312974
• RGDID: 1311921
• Length: 2985
• Species: Rattus norvegicus
• Sequence 2: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Alignment Length: 4459
• Identity: 1247/4459 - (27%)
• Similarity: 1719/4459 - (38%)
• Gaps: 1697/4459 - (38%)

  Rat    14 GNIFSEGLEGLGECGYPENP-----VNPMGQQMPIDQGFPSLQPSLHH-PSPNQNQTKLTHFDHY 72
            ||  |.|..|..:..:.:.|     .:|:.||.         .|::|| ..|....|:.|
  Fly   655 GN--SSGATGGAQNQHQQQPQLAAMSSPLHQQN---------LPNMHHLIQPTMETTQPT----- 703

  Rat    73 NQYEQKMHLMDQPNRMMGSAPGNGLASPHSQ--YHTPPV---PQVPHGGGSGGGQMGVYPGMQND 132
            .|.:|......||.:     |...|.|||.|  .|..|:   .|.||                :.
  Fly   704 QQQQQTSQQQQQPQQ-----PQATLTSPHHQQMQHQSPIHQQQQSPH----------------HQ 747

  Rat   133 RHGQSFVDGGSMWGPRAVQVPD-QIRAPYQQQQPQPAPSGPPAQGHPQHMQQMGSYLARGDFSMQ 196
            :|..|:......:.|.|..:.| |..|..|...|....|..|||     |||. .:..:...|.|
  Fly   748 QHLPSYNQSQQQFDPFANILGDNQPAASQQTMSPAHVSSPVPAQ-----MQQQ-QHQTQQQPSQQ 806

  Rat   197 QPQQRMSQFSQGQEGLSQGSPFIATSGPGGHLSHMPQQSPNIAPSLRHPVQQQ------------ 249
            .||.:..|.||.|:...|..|    |.|..|||.:..::.|...|....|...
  Fly   807 VPQSQQQQVSQPQQQTQQQQP----STPSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTN 867

  Rat   250 --FHHHPAALHGESVAHSPRFSPNPPQQ---------GAVRPQTLN------------FSSRSQT 291
              .::.|.::|..:...|...|.|..||         |.......|            .||.|..
  Fly   868 SIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNSHGGNSESAQNAGVDVGLFDNNSMSSNSAA 932

  Rat   292 VPSPTVN---------NSGQYSPYPYRNLNQ------GLV--------------NSTGMNQNLGL 327
            |.:...|         :|...|.......||      |:|              ||....|::.|
  Fly   933 VAAVASNAASAAAALLDSNSQSSNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSVSKTQDITL 997

  Rat   328 TNSTP-MNQSVPRYPNAVGFPSNSGQGL------MLQQP--IHSSG-SLNQMNTQTMHPSQPQGT 382
            :...| :...:...|.|....:..||.|      :|::|  :..|| ..:|.......|:.|...
  Fly   998 STELPTIQDDLQEKPTAEMEQTQLGQSLGDLSKSLLEEPKTVEESGEDKSQSAPGVAPPADPIIP 1062

  Rat   383 YASPP---------PMSPM----KAMSNPAGTPPPQVRPGSAGIPMDVGSYPNMPHPQPSHQ--- 431
            ...||         ||.|:    :|.:...|..||.: |...|.|   |.||  |:|....|
  Fly  1063 VTQPPQQQMPPIGMPMHPIAPGYEAQAQGQGHMPPMM-PPYGGAP---GMYP--PYPMLHQQEIA 1121

  Rat   432 ------------PPGAMGIGQRNMGPRNIQQPRPFMGMSSTPRELTGHMRPNGCPGVGLADAQAI 484
                        |||           ..:|.....|.|......||.|...:.|.|    ..|.:
  Fly  1122 ALQQQIQELYCMPPG-----------HELQHQDKLMRMQERLNLLTQHEVNDQCAG----GPQCL 1171

  Rat   485 QERLIPGQQHPGQQPPF-QQLPTCPPLQPHPGLHQSSPPHPHHQPWAQLHPSPQNTPQKVPVRQH 548
            ..:.:|....|...|.. ||:...|.:....|..:....:...:|.|:       ..:|..|.|.
  Fly  1172 LFQNVPPMYGPPGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAK-------KGEKAQVGQQ 1229

  Rat   549 SPSEPFLEKPVPDMTQVSGQNA-------------QLVKSDDYLPSIEQQPQQKKKKKKNNHIAA 600
            .           |:..:||..|             ||..|:|.:..                 .|
  Fly  1230 Q-----------DLMDISGNVAMGAANAVSSIPTTQLPVSEDCVTQ-----------------GA 1266

  Rat   601 GDPSKGFGKDDFPGGVD--NQEL-SRNSLDASQEETKKRKRPKVKKDPKELKEPREKKEPKTPKA 662
            ||.|. .|..::..|:.  :|:: |.|.||.|.:.:.|:|:|:..:.||:..:|...:.||. |.
  Fly  1267 GDTSV-VGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKKPRKPRTPKDPNKPPRDRTPKA-KK 1329

  Rat   663 PKTPKEP----------------KERKA------------------KTVTPK------------- 680
            ||.|.:|                |.||.                  |.:.||
  Fly  1330 PKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGEGSEVEDNKPLVPKAGSADGEAETTSG 1394

  Rat   681 -------------------PKSSKKSSNKK----------PDS---------------------- 694
                               |:.|.:...:.          |||
  Fly  1395 GTGVDGESPDYDDIPVSKIPRGSNEDEKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRR 1459

  Rat   695 -----------------EASALKKKVNKGK----TEGSENSDLDKTPPPSPGPEEDEDPGVQKRR 738
                             .|.||||:.|:|:    ::| |:..||:||||||.|:.:.|.  .|||
  Fly  1460 NANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDG-EDDTLDRTPPPSPPPDSEMDS--NKRR 1521

  Rat   739 SSRQVKRKRYTEDLEFKISDE--------------------------------------EADDAD 765
            |||..:||:|.:|:..:.||:                                      |.|.|.
  Fly  1522 SSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASNSNAGSDVEKTEPQSGAEGDAAQ 1586

  Rat   766 AAGRD----------------SPSNTSQSEQQESVDA-------------------EGPVVEKIM 795
            ..|.:                |.|..::.|:|.|.||                   :..||:.::
  Fly  1587 EVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVL 1651

  Rat   796 SSRLVK----------------------------------------------------------- 801
            :.|:.|
  Fly  1652 AMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESS 1716

  Rat   802 ----------------------------------------------------------------- 801
                                                                             
  Fly  1717 AMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSS 1781

  Rat   802 -----------------------------------------------------KQKES------- 806
                                                                 |.|||
  Fly  1782 TVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEK 1846

  Rat   807 -----GEE----------------------VEVEEFYVKYKNFSYLHCQWASVEDLEK-DKRIQQ 843
                 |||                      ::|||::|||:|||||||:|.:.|:|.| |:|:..
  Fly  1847 ERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAA 1911

  Rat   844 KIKRFKSKQGQS-KFLSEIEDDLFNPDYVEVDRIMDFARSTDD-RGEPVTHYLVKWCSLPYEDST 906
            ||:||:.||.|. .....|||:.||.|:.||||::|.:..||: .||...||||||.||||||.|
  Fly  1912 KIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCT 1976

  Rat   907 WELRQDLDQAKIEE---FEKLMSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWL 968
            |||.:|:|..|||:   |.|:..|. |.:..:||..:.|||.|.:..||..|.||.|||||:|||
  Fly  1977 WELEEDVDNDKIEQYLRFNKIPQRS-EWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWL 2040

  Rat   969 LFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVV 1033
            .|:|||..||||||||||||||||:||::.:|..||.|||||||||||||||:|||..||::|||
  Fly  2041 KFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVV 2105

  Rat  1034 VYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHR 1098
            |||||..|::.||.||.|:|...|:|:|...||:.:|||||||:||..:|:...||..|||||||
  Fly  2106 VYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHR 2170

  Rat  1099 LKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQ 1163
            ||||||||||||:.::|||:|||:||||||.:.||||||:|||||:|.|:..||.|||.|:|||:
  Fly  2171 LKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEE 2235

  Rat  1164 VQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVP 1228
            |.||||:||||||||||:||||:||||||||||||||||||||||.|||:||:||.||...||:|
  Fly  2236 VNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTSANIP 2300

  Rat  1229 NLLNTMMELRKCCNHPYLINGAEEKILEEFKDAHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKA 1293
            ||:||||||||||.||||:|||||:|..:||..|..| |:...:.:|.:|||:||||||||||||
  Fly  2301 NLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHGED-PESYYKNLILSAGKMVLIDKLLPKLKA 2364

  Rat  1294 GGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAG 1358
            .|||||||||||||||||||||:.|:||:||||||:||||||.||||:|||.||||||||||:||
  Fly  2365 NGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAG 2429

  Rat  1359 GLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGL 1423
            |||||||||||.||:|||||||||||||||||||||.|.||||||:.||:||||||||||:||||
  Fly  2430 GLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGL 2494

  Rat  1424 DKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTIT 1488
            ||||||||:.:.:.....:|||||||||||:||||||:||:::.|.||||||||.||.|||..||
  Fly  2495 DKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVIT 2559

  Rat  1489 IESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDAL--NGRNNLVIDTPRVRKQT 1551
            :||| |||||:||||.|||||:||::|||:||.|||||.::|.||.  :...:||:..||.|.|.
  Fly  2560 MESE-KGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQI 2623

  Rat  1552 RLYSAVKEDELMEFSDLESDSEEKP-----CIKPRRPQDKTQ----------------------- 1588
            :.|.   .:::||.:..||.:|...     .::.||.::|..
  Fly  2624 KRYG---HEDVMELNSEESSNENSDEEGGIGLRSRRRKEKRDRAREKKGNDEYIPRERDALAALG 2685

  Rat  1589 -------GYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEHDVETICRAILVYCLNHYRGD 1646
                   .:|:||||:|||.||.:|||||:::|..|::||...:.|||...|.||:|||..|:||
  Fly  2686 LEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLELGQFKRGWRDVDVEDCARIILLYCLQVYKGD 2750

  Rat  1647 ENIKSFIWDLITPTADGQTRAL-LNHSGLSAPVPRGRKGKK------------------------ 1686
            |.||:|||||||||.||:.:.: .:||||...|||||.|.|
  Fly  2751 EKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKESTGVSTPAPGSASGSNSGNT 2815

  Rat  1687 ------------------VKAQSMQPVVQDA----DWLASCNPDA-LFQEDSYKKHLKHHCNKVL 1728
                              :.|.::...|...    .|......|| .:.|.:|||||..|.||||
  Fly  2816 TPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVL 2880

  Rat  1729 LRVRMLYYLRQEVIGDQAEKILEGADSSEADVWIPEPFHAEVPADWWDKE-ADKSLLIGVFKHGY 1792
            ||||||||::.|||||..::|.:....||..: .|.|...:||:.||:.. .|||||:|.:|||.
  Fly  2881 LRVRMLYYIQHEVIGDFVQQIKDNTPISELPI-RPPPTPDQVPSSWWNPICCDKSLLVGTYKHGC 2944

  Rat  1793 EKYNSMRADPALCFLERVG---MPDAKAIAA------------------EQRGTDMLAD------ 1830
            |.|..|||||.|||:..||   ..|..|:.:                  :..||....|
  Fly  2945 EMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKL 3009

  Rat  1831 -GGD-----------------------GGEFDREDEDPEYKPTRAPFKDEI-------------- 1857
             |||                       ||....|.|:.....:.:.:|.|:
  Fly  3010 TGGDNKDSLLDPERPSSSGKSSSENASGGNDKTESENDATTVSESSYKSEVLPGKGSDLDVSVAQ 3074

  Rat  1858 -------DEFANS--PPEDKEDSM-------------------EAQSTG---------------- 1878
                   .|.||:  |..:|.|:.                   :||.||
  Fly  3075 QDALSATPELANTSDPKMNKNDAQVSASVSCDPADSSSPEAAGKAQGTGVQTGDAGELDIESEKK 3139

  Rat  1879 ----------------------------------------------------------------- 1878
                                                                             
  Fly  3140 DNEKETKESTGDAPAVEAKKDSAAIARAEGDKTESCTNNATTNISTTTTTTTITNTTTTTNNPSS 3204

  Rat  1879 ---------KHSESNAELG---------------------QLYWPNTSSLTTRLRRLITAYQRSY 1913
                     .|:.||:.||                     ...||:...|.|||||:||||||:|
  Fly  3205 KAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNY 3269

  Rat  1914 KRQQMR-------------------------------------------------------QEAL 1923
            |:::::                                                       .:||
  Fly  3270 KKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGSGIGSSAQHDASGRSLQAL 3334

  Rat  1924 MKT-------------------------------------------------------------- 1926
            |::
  Fly  3335 MQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGAGVMPAMPTAADISLMLSILNTTDVNQLANLD 3399

  Rat  1927 ------------DRRRRRPREEVRALEAEREAIISEKRQ----KWTRREEADFYRVVSTFGV--- 1972
                        ::..|:.:.|:.|.|.|     |::.|    ||.||||.:|.||::.:||
  Fly  3400 INKLAMYLVSMNNKMERQGKMELAAKERE-----SQRLQLIPKKWNRREEYEFLRVLTGYGVDLH 3459

  Rat  1973 IFDPVKQQF------DWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPAKPEDEPPDLASL 2031
            :..|:....      ||.:|:..|.|::||||:|..|:..|||||:|...:  |..:....|..:
  Fly  3460 VSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDYYKVFVAMCKRQAGL--KLSESERGLEGI 3522

  Rat  2032 IEPITEERASRTLYRIELLRKIREQVLHHPQLSDRLKLCQPSLDLPEWWECGRHDRDLLVGAAKH 2096
            ||.|.:|.|...|.|:|:|.|:|| |..:|.|.:|||||..:.|.|:|||.||||::|:....||
  Fly  3523 IEEIEKEHAKLILDRLEVLAKLRE-VARNPMLEERLKLCTKNADTPDWWEPGRHDKELITAVLKH 3586

  Rat  2097 GVSRTDYHILNDPELSFLDAHKSFAQNRGASTVPSLNTLAMGFGQAPPVIAS--------AHAHE 2153
            |:.|::..|.|||..||.::.|.|.:...|....::...|....:|..:.|:        |.|.|
  Fly  3587 GLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKDAATEKAAATE 3651

  Rat  2154 EKVMEQA---------------------------------------------------------- 2160
            :...|:|
  Fly  3652 KAAAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKHDTADNLEDKNSDAEE 3716

  Rat  2161 ---------------------------------------------------------------EG 2162
                                                                           ||
  Fly  3717 STKIKGKEDFNPETTEKEALDESTNLNKDKSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEG 3781

  Rat  2163 KAEECEHSPAKERS----------DGKEEEEEAG-GAKDSRQECEAEASSVKGEL--KGVEGSGD 2214
            ..|:|..:..|:.|          |||..|.||. .|.::.:.|..::.|.:.|.  |.||...:
  Fly  3782 SPEKCSDAEDKKFSEEKPSSPAVPDGKVSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEE 3846

  Rat  2215 PGSKSVSEKGSEEDEE-EKL-------EDDDKSEESSQPEAGAVSRGKTFDEESNASMSTARDET 2271
            ...::..||..|:.|| |||       |..:|||...:||. ||.:..|.|::. ..:.....:.
  Fly  3847 EKGENSYEKAEEQKEETEKLEKSSIESEPSEKSETVLEPEV-AVPKKSTGDQDI-LDLVAGPSDP 3909

  Rat  2272 RDGFYMEDGDPSVAQLLHERT-----------------------------FAFSFWPKDRVMINR 2307
            .|...|::.:.:|.:...::.                             .....|.||..:..|
  Fly  3910 DDDEVMKEKEKAVEEECKKQAAELKARFPDLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERR 3974

  Rat  2308 LDNICEAVLKGKWPINRR------------------------QMFDFQGLVPGYPPSTVDSPLQK 2348
            :.:|...|..|.||::.:                        ...:.:...|.....|.|..:.|
  Fly  3975 IAHIVACVESGNWPVDSKYSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTK 4039

  Rat  2349 RSFAELSMVSQASVSASEDITTS--PQL--SKDDALN---------------------------- 2381
            .  .:.|.:.|.:.|||...|:|  ||:  ||..:.|
  Fly  4040 H--LQTSHMQQVASSASAASTSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNAT 4102

  Rat  2382 ------------------------LSVPR------QRRRRRRKVEIEAERAAKRRNLMEMVAQLR 2416
                                    ||||.      ::|:|...:::|.|||       ::.|.|.
  Fly  4103 SLSSLLPGMSLSAATGSSAGGVSGLSVPSAGSGVGKKRKRHIAIDVETERA-------KLHALLN 4160

  Rat  2417 ESQVVSENGQEKVVDLSKAS------REATSSTSN---------FSSLT-------SKFILPNVS 2459
            .|.:..::.:.::.::...|      |...||.|:         .:||:       ||..:|.:.
  Fly  4161 SSTMAPKDWESEIANMEALSGSSGRGRGGNSSASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMK 4225

  Rat  2460 TP----------VSDAFKTQM-ELLQAG-------------LSRTPTRHVLNGSLVDGEPPMKRR 2500
            ||          .|...|..| |:|::.             .|....:..::.:|....|.|..:
  Fly  4226 TPPPSMGAPMDLSSSLPKMNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNK 4290

  Rat  2501 R----------------------GRRKNVEGLDLLFMSHKRTPLSAEDAEVTKAFEEDIETPPIR 2543
            .                      |:.|..:.||.:.:.     |||  |:..|.|.:    |.:.
  Fly  4291 SKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLG-----LSA--AKEQKTFPD----PSLP 4344

  Rat  2544 NIPSPGQLDPDTRIPVINLEDGTRLVGEEAP---------------------------------- 2574
            :...| |:.|...:...||:..:.....:.|
  Fly  4345 SSKKP-QIPPSVSVTPANLQSSSNQQSNQKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGA 4408

  Rat  2575 ----------------KNKDLVDWL---------------------------------------- 2583
                            .:||.::.|
  Fly  4409 GGSGLSALQNMAMGGLSSKDSLNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQ 4473

  Rat  2584 --KLHPMYTVDMPSYVPKN---ADVLFSPF----------------------------------- 2608
              |:...::.:.|..|..|   :| :.||.
  Fly  4474 AMKISSKFSTNSPHDVKVNKWLSD-MTSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQS 4537

  Rat  2609 ---------------QKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLP 2658
                           |:.:|::|....|     ..|||||.|||:||:.||::||..||.:|.|.
  Fly  4538 SSAAQLQKQQQQQQQQQQQQQQHSMPGP-----QNLTGEEPVPVINKQTGKRLGGNKAPQLKRLM 4597

  Rat  2659 RWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGAS---RRGRRPKSEIA------ 2714
            :||.|||.:.|.|.|.:.::.....|...     ...:..|.|:|   ..|.||.|.::
  Fly  4598 QWLTENPNYEVDPKWLEQMQNPMSTPSPR-----PASMESGYGSSAVKSHGGRPLSNLSSTSSSS 4657

  Rat  2715 ----RAAAAAAAVASTSGI---NPLLVNSLFAGMDLTSLQ--NLQNLQSLQLAGLMGFPPGLATA 2770
                :::||.:.....||.   |.....:..|.:|..:||  :|..|....||.|    |||...
  Fly  4658 HTQQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAALQFGSLAGLNPSLLANL----PGLGAF 4718

  Rat  2771 ATAGGDAKGPAAVL----PLM------LPGMAGLP--------NVF----GLGGLLN-------- 2805
                 |.|.|.|..    ||:      :|||..:|        |:|    |:|||.|
  Fly  4719 -----DPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQS 4778

  Rat  2806 -NPLSAATGNT---------------TTASSQGEPEDGTSKAEEKGNDNEDENRDSEKS--TDAV 2852
             ..|.||.|.|               :.|.||......:|.|.:|....:.:...:|.:  ..|:
  Fly  4779 LAALMAAAGPTLGGLTGASGGAGSGKSQAQSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAI 4843

  Rat  2853 SAADSANGSVGAATAPAALPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFPALAGLQN 2917
            ||:...:|:.|...| ||..|...|..|||...  |.|.||    |.|||||.    |...| .:
  Fly  4844 SASTGGSGASGGKNA-AASASQLAAGFPFLFPN--PSLLYP----PMGLGGLN----PYSLG-SS 4896

  Rat  2918 AVGASEEKAADKAEGGPCKDGETLEGSDAEENLDKTIES 2956
            .:|::.::.|.:..   ..:|.|...|:......|:.:|
  Fly  4897 GLGSAYDQLAQQYN---LLNGATSSASNTSSTQSKSHQS 4932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd7	NP_001101376.2	Med15	<2..>318	CDD:312941	84/379 (22%)
		Atrophin-1	194..>567	CDD:460830	98/475 (21%)
		CD1_tandem_CHD5-9_like	785..849	CDD:349315	35/294 (12%)
		CD2_tandem_CHD5-9_like	868..925	CDD:349310	33/60 (55%)
		PLN03142	956..>1555	CDD:215601	429/600 (72%)
		BRK	2551..2592	CDD:462196	8/132 (6%)
		BRK	2630..2674	CDD:197800	24/43 (56%)
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941	52/264 (20%)
		PRK12678	1319..>1500	CDD:237171	28/182 (15%)
		PTZ00121	<1419..1923	CDD:173412	81/506 (16%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	26/66 (39%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	31/57 (54%)
		PLN03142	2029..>2606	CDD:215601	423/578 (73%)
		PTZ00341	<3662..3887	CDD:173534	32/224 (14%)
		BRK	4568..4611	CDD:462196	24/42 (57%)