DRSC/TRiP Functional Genomics Resources

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Protein Alignment N and HAPLN2

DIOPT Version :9

Sequence 1:NP_001245510.1 Gene:N / 31293 FlyBaseID:FBgn0004647 Length:2703 Species:Drosophila melanogaster
Sequence 2:NP_068589.1 Gene:HAPLN2 / 60484 HGNCID:17410 Length:340 Species:Homo sapiens


Alignment Length:158 Identity:37/158 - (23%)
Similarity:47/158 - (29%) Gaps:56/158 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly  1349 GGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEHCEI 1413
            ||...:|: ||....:....|...|                   ||| .||||...|...|...:
Human    98 GGRARMRR-GHRLDASLVIAGVRLE-------------------DEG-RYRCELINGIEDESVAL 141

  Fly  1414 DTLDE--CSPNPCAQG----------AACEDLLGDYECLCPSKWKGKRCDIYDANYPGWNGG--- 1463
            ....|  ..|...::|          .|||:..|             |...|...|..|..|   
Human   142 TLSLEGVVFPYQPSRGRYQFNYYEAKQACEEQDG-------------RLATYSQLYQAWTEGLDW 193

  Fly  1464 --SG---SGNDRYAADLEQQRAMCDKRG 1486
              :|   .|:.||  .:...||.|..||
Human   194 CNAGWLLEGSVRY--PVLTARAPCGGRG 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NNP_001245510.1 EGF_CA 179..214 CDD:238011
EGF_CA 217..252 CDD:238011
EGF_CA 260..291 CDD:238011
EGF_CA 295..329 CDD:238011
EGF_CA 331..369 CDD:238011
EGF_CA 449..486 CDD:238011
EGF_CA 488..524 CDD:238011
EGF_CA 526..562 CDD:238011
EGF_CA 564..600 CDD:238011
EGF_CA 602..637 CDD:238011
EGF_CA 640..675 CDD:238011
EGF_CA 677..713 CDD:238011
EGF_CA 715..750 CDD:238011
EGF_CA 753..789 CDD:238011
EGF_CA 791..827 CDD:238011
EGF_CA 829..865 CDD:238011
EGF_CA 907..943 CDD:238011
EGF_CA 946..982 CDD:238011
EGF_CA 984..1020 CDD:238011
EGF_CA 1027..1058 CDD:238011
EGF_CA 1062..1095 CDD:238011
EGF_CA 1184..1219 CDD:238011
EGF_CA 1221..1257 CDD:238011
EGF_CA 1259..1295 CDD:238011
EGF_CA 1297..1335 CDD:238011
EGF_CA 1417..1450 CDD:238011 7/44 (16%)
NL 1476..1512 CDD:197463 5/11 (45%)
Notch 1519..1553 CDD:278494
Notch 1565..1593 CDD:278494
NOD 1599..1648 CDD:284282
NODP 1680..1731 CDD:284987
ANK 1896..2038 CDD:238125
ANK repeat 1902..1948 CDD:293786
ANK repeat 1951..1981 CDD:293786
Ank_5 1970..2025 CDD:290568
ANK 1978..2104 CDD:238125
ANK repeat 1984..2015 CDD:293786
ANK repeat 2017..2048 CDD:293786
Ank_2 2022..2114 CDD:289560
ANK repeat 2050..2081 CDD:293786
ANK repeat 2083..2114 CDD:293786
DUF3454 2627..2682 CDD:288764
HAPLN2NP_068589.1 Ig 49..149 CDD:386229 17/71 (24%)
Link_domain_HAPLN_module_1 148..241 CDD:239595 20/87 (23%)
Link_domain_HAPLN_module_2 250..337 CDD:239596
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22804
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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