DRSC/TRiP Functional Genomics Resources

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Protein Alignment kirre and bcam

DIOPT Version :10

Sequence 1:NP_525059.2 Gene:kirre / 31292 FlyBaseID:FBgn0028369 Length:956 Species:Drosophila melanogaster
Sequence 2:NP_001352817.1 Gene:bcam / 767689 ZFINID:ZDB-GENE-060929-620 Length:611 Species:Danio rerio


Alignment Length:633 Identity:148/633 - (23%)
Similarity:236/633 - (37%) Gaps:158/633 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 GSRVTLPCRV---MEKVGALQWTKDDFGLGQHRNLSGFERY-SMVGSDE---------EGDFSLD 147
            |..|.|||..   .|...|:||. .:|..|..:.::    | |.||||.         |.|.||:
Zfish    40 GDTVMLPCTYTTSAEAAVAVQWF-IEFADGGRKQVA----YKSSVGSDAGTFTDRYTIEKDMSLN 99

  Fly   148 IYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKIT---QGDYLVTTEDREIEL-E 208
            |..:.:||..|:.|||..||   .|......::.|...||.|.:.   |..::.::.....|: :
Zfish   100 ISQVTVDDHKKFICQVTAGP---VGTAESATEVKVFSAPEKPMVVPNPQKIFVDSSISSSAEVGK 161

  Fly   209 CVSQGGKPAAEITWIDGLGNVL---------TKGIEY-VKEPLADSRRITARSILKLAPKKEHHN 263
            |:|:.|.|...|.|... .|.|         |..|.: |||.   |...|..|:|.:...|....
Zfish   162 CISRNGHPEPRIIWFKD-DNPLPEEKKKTEKTYMIHFLVKEA---SGLYTLTSMLYMHLTKADAK 222

  Fly   264 TTFTCQAQNTAD----RTYRSAKLLLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPH 324
            :.:.|..:.|..    :...|....:.::|:.:.:...|...   |.|.||.:|::.|:.|.|| 
Zfish   223 SVYHCIVEYTMPDNQIKQESSDNFNISLQYSTENVFFKVKNE---GPIKEGDDVVMQCETDGNP- 283

  Fly   325 ELSYRWFINDELMT---GDFTTKMIIHNVSRQYHDAIVKCEVVN--AVGKSEQSKKLDISFGPVF 384
            :..:.:|..::|:.   |....|.|....|..|     |||.::  |..|.:..|.|:|:...: 
Zfish   284 QPQFDFFKGEKLLEGLGGTLKKKSITREDSGTY-----KCEAMDYEADSKVQLHKTLNINVHYI- 342

  Fly   385 RQRPVSVEAD------LGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKLKVSSETAGRYF 443
               .::||.:      .|..|.::|....:....::| :::|.::.......|..|:....|.|.
Zfish   343 ---DITVEPEGPLVVSKGDHVELQCKAKASEAHTLQW-TKDSKELSNTGVFAKESVTLADGGVYV 403

  Fly   444 CKAVVNGFPEIGAEA--TLYVKRAPIITSH-KVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKI 505
            |...|...|.:..:.  |:.||..|.|.:. |......||.|.::|.|...| |...:|:..|| 
Zfish   404 CVGAVPSVPGLQKQVNITVNVKGQPEIDAPVKGLVDKEGGMVTLNCSALGHP-APQFIWTPSGK- 466

  Fly   506 INMSSADPDIYIFEEHHLPEGVR---------AALIIRDSKATHFGKYNCTVMNSYGGDSLVITL 561
                          |....:|.|         .|.:::|...       |...|::|.||     
Zfish   467 --------------ESVTVKGNRVISTVTLEATAAVLKDGVI-------CEAYNTHGRDS----- 505

  Fly   562 LREPGNIPVLL-----------------------------VVMGSMFCVAIILMIVMIIIVYRKR 597
                .|..|.|                             ||:..:.||.::|::|..:....|:
Zfish   506 ----KNFEVKLDQAKPTPANSDRGNPDFKTVEGKQGGSSSVVIAVVVCVLLLLILVASLFFLNKK 566

  Fly   598 RS---RKKPMPADVIPEASRGGDKLN---ELKSELRSKAYDVEYSEAG 639
            ..   .||..     .|.:.||.|.|   |:|...:||      .|||
Zfish   567 GKLGCGKKDQ-----KEVASGGVKDNIVVEIKPSEKSK------EEAG 603

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kirreNP_525059.2 IG_like 88..182 CDD:214653 31/98 (32%)
Ig strand B 99..103 CDD:409552 2/3 (67%)
Ig strand E 144..148 CDD:409552 2/3 (67%)
Ig strand F 158..163 CDD:409552 2/4 (50%)
C2-set_2 189..279 CDD:400489 23/107 (21%)
Ig strand C 219..223 CDD:409416 1/3 (33%)
Ig strand E 251..255 CDD:409416 2/3 (67%)
Ig strand F 265..270 CDD:409416 1/4 (25%)
Ig strand G 280..283 CDD:409416 1/2 (50%)
Ig_2 307..379 CDD:464026 22/76 (29%)
Ig 382..462 CDD:472250 15/87 (17%)
Ig strand B 399..403 CDD:409353 1/3 (33%)
Ig strand C 412..417 CDD:409353 1/4 (25%)
Ig strand F 441..446 CDD:409353 2/4 (50%)
Ig strand G 455..458 CDD:409353 0/2 (0%)
Ig 466..561 CDD:472250 23/104 (22%)
Ig strand B 482..486 CDD:409353 1/3 (33%)
Ig strand C 496..500 CDD:409353 0/3 (0%)
Ig strand E 529..533 CDD:409353 1/3 (33%)
Ig strand F 543..548 CDD:409353 1/4 (25%)
Ig strand G 556..559 CDD:409353 1/2 (50%)
bcamNP_001352817.1 Ig 27..131 CDD:472250 31/98 (32%)
Ig strand B 43..47 CDD:409353 2/3 (67%)
Ig strand C 59..62 CDD:409353 1/2 (50%)
Ig strand E 96..100 CDD:409353 2/3 (67%)
Ig strand F 110..115 CDD:409353 2/4 (50%)
Ig strand G 124..127 CDD:409353 0/2 (0%)
Ig 138..234 CDD:472250 23/99 (23%)
Ig strand C 172..176 CDD:409353 1/3 (33%)
Ig strand E 191..195 CDD:409353 1/3 (33%)
Ig_3 267..320 CDD:464046 17/58 (29%)
Ig_2 351..422 CDD:464026 12/71 (17%)
Ig_3 428..499 CDD:464046 19/93 (20%)

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