DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and dpr12

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	56/267 - (20%)
Similarity:	102/267 - (38%)	Gaps:	51/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 GKSEQSKKLDISFGPVFRQRPV---SVEADLGATVSMRCDVAGNPE-----PEIEWISENSDQVV 424
            |.|:....||.|..|:|....:   :....||.|..:.|.|:|...     .:|.||......::
  Fly    61 GDSKLDNNLDSSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHIL 125

  Fly   425 GVAAE--------------------LKLK-VSSETAGRYFCK-----AVVNGFPEIGAEATLYVK 463
            ...|:                    |::| |.....|.|.|:     .:::.|..:    .:.|.
  Fly   126 SSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNL----QVVVP 186

  Fly   464 RAPIITSHKVQFGGVGGRVKIDCLAFSIP-KAEHILWSFEGKIINMSSADPDIYIFEEHHLPEGV 527
            .|.|:.|.::.. .:|..:.:.|:....| ..:::.|....::||...:..||.| |....|. .
  Fly   187 EAFILGSGELHV-DMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITI-ETTPGPR-T 248

  Fly   528 RAALIIRDSKATHFGKYNCTVMNS---------YGGDSLVITLLREPGNIPVLLVVMGSMFCVAI 583
            ::.||||:.:.|..|.|.|:..|:         ..||::.....|:..:...|..:..||....:
  Fly   249 QSRLIIREPQVTDSGNYTCSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLTHIFRSMLAPCL 313

  Fly   584 ILMIVMI 590
            :|..|::
  Fly   314 LLNTVVV 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845
		IG_like	88..182	CDD:214653
		C2-set_2	189..279	CDD:285423
		Ig_2	307..379	CDD:290606	4/10 (40%)
		I-set	382..462	CDD:254352	19/113 (17%)
		IGc2	396..446	CDD:197706	15/80 (19%)
		Ig	466..561	CDD:299845	24/104 (23%)
		IG_like	478..561	CDD:214653	22/92 (24%)
dpr12	NP_652462.3	IG	86..183	CDD:214652	17/100 (17%)
		Ig_3	193..271	CDD:404760	20/80 (25%)
		Ig strand B	204..208	CDD:409353	0/3 (0%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810