DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and CG7166

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	76/308 - (24%)
Similarity:	126/308 - (40%)	Gaps:	61/308 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 VVGSRVTLPCRVMEKVGA--LQWTKDDFGL-GQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDD 155
            :||..:.|||:| :.:|:  |.|.|....| ..|..::..:|:.:|     ||::|.|..:...|
  Fly    51 IVGETIELPCKV-QNLGSFVLLWRKGSSVLTAGHLKITRDQRFKIV-----GDYNLQINGVKTQD 109

  Fly   156 DAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEI 220
            ...|.||:     |:|..|.:...:.:||||....:.....:...:...:.||| ...|.|...|
  Fly   110 AGDYICQL-----GDQENRDQVHTVEILVPPTLRALPHNGQVTARKGSTVTLEC-KASGNPVPTI 168

  Fly   221 TWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQN-TADRTYRSAKLL 284
            .|             :.|:..:....::..|.|.|.....||..|:.|.|.| ..||.  |..:.
  Fly   169 FW-------------FKKDVFSGPTHLSDSSTLILENVDRHHAGTYQCSADNGVKDRV--SMDIQ 218

  Fly   285 LEVKYAPKVIV--SVVGGALAGGKIPEGAEVILSC--QADANPHELSYRWFINDELMTGDFTTKM 345
            |.:...|::.|  |.|..:       ||.:|.|.|  ..|.|...|   |:.|..|:  |.|.:.
  Fly   219 LTILSPPEITVEKSWVHAS-------EGYDVELVCIVHGDVNSEML---WYQNSFLL--DATDRR 271

  Fly   346 IIHNVSRQYHDAIVK-----------CEVVNAVGKSEQSKKLDISFGP 382
            .::....:| ..|::           |...||:|:::  |.:::|..|
  Fly   272 SMYPRDDRY-SLIIRNFQPTDFGNYSCVADNALGRTK--KYIEVSGRP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	25/91 (27%)
		IG_like	88..182	CDD:214653	25/90 (28%)
		C2-set_2	189..279	CDD:285423	19/90 (21%)
		Ig_2	307..379	CDD:290606	20/84 (24%)
		I-set	382..462	CDD:254352	1/1 (100%)
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	25/92 (27%)
		Ig	56..116	CDD:143165	18/65 (28%)
		IG_like	144..221	CDD:214653	21/92 (23%)
		IGc2	151..209	CDD:197706	17/71 (24%)
		IG_like	232..313	CDD:214653	22/95 (23%)
		Ig	242..311	CDD:143165	18/76 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810