DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and dpr20

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	71/349 - (20%)
Similarity:	121/349 - (34%)	Gaps:	113/349 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KKNKSSQ--SSHHGDSSSSSSSSSSSSG-SSSAAASSANDESKPKGGDNG--------------- 80
            |||.|.|  .|.:.::...::.:::||| .||:.||.|......:....|
  Fly   168 KKNASFQQIGSQNVNALVPATVATTSSGLPSSSNASLATPTEPARNRSTGLVRNSAVKVDSKHPL 232

  Fly    81 -------------------------------GQHF-----AMEPQDQTAVVGSRVTLPCRV---M 106
                                           |.||     ..:..:.|...||.:.|.||:   .
  Fly   233 SKGQKTDAPMLNYIFDTFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQ 297

  Fly   107 EKVGALQW----TKDD----------FGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDA 157
            :|  .:.|    |:|:          ..:|.| ..:|.:||.| ......::.|.|..:..||:|
  Fly   298 DK--TVSWVRHNTQDEGKDNGNALDLLTVGMH-TYTGDKRYKM-EFQYPNNWRLKITNVKKDDEA 358

  Fly   158 KYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKI----TQGDYLVTTE---DREIELECVSQGGK 215
            .|:||:...|       .|..::.:.|  .|||:    ..||.|....   |..::|.||.:...
  Fly   359 IYECQISTHP-------PRVIQINLHV--NAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVA 414

  Fly   216 PAAEITWIDGLGNVL----TKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADR 276
            ..:.:.:...:.|:|    |:|...||..|.:.   .|.|.|.:|...:..:..:||......:.
  Fly   415 MTSSVVFWKHMDNILNYDVTRGGVSVKTELMED---GANSTLSIAKISKTDSGNYTCSISEFQNF 476

  Fly   277 TYRSAKLLLEVKYAPKVIVSVVGG 300
            |               ::|.::.|
  Fly   477 T---------------IVVHILNG 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	26/112 (23%)
		IG_like	88..182	CDD:214653	26/110 (24%)
		C2-set_2	189..279	CDD:285423	23/100 (23%)
		Ig_2	307..379	CDD:290606
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	24/90 (27%)
		Ig	279..378	CDD:299845	26/109 (24%)
		Ig	400..471	CDD:299845	17/73 (23%)
		IG_like	402..480	CDD:214653	17/95 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810