DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and dpr19

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	377	Identity:	75/377 - (19%)
Similarity:	121/377 - (32%)	Gaps:	108/377 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 VGKSEQSKKLDISFGPVFR-----QRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQV--V 424
            |||...|:.   .||...:     :....|.|..|....:.|.|..|....:.||.....|:  |
  Fly    24 VGKITSSQN---HFGNTLQSQFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTV 85

  Fly   425 GVAA------------------ELKLK-VSSETAGRYFCK-------------AVVNGFPEIGAE 457
            |::.                  .|::| |..|..|.|.|:             .:|....||.:.
  Fly    86 GLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIYPTQSIVIELKIVEAVAEISSA 150

  Fly   458 ATLYVKRAPIITSHKVQFGGVGGRVKIDC-LAFSIPKAEHILWSFEGKIINMSS----------- 510
            ..|::...              ..::::| |..:......:.|..:.|:||..|
  Fly   151 PELHIDET--------------STLRLECKLKRATENPAFVFWYHDSKMINYDSQGGFVVTSIGQ 201

  Fly   511 ADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYGGDSLVITLLREP-GNIPVLLVV 574
            ::|....|.........||.:.:..|..         |:||..|.|   ..::.| .|:|.....
  Fly   202 SNPQSGQFYRSSPANKSRATMPMESSNG---------VLNSLLGSS---DAIKAPAANVPSSTPY 254

  Fly   575 MGSMFCVAIILMIVMIIIVYRKRRSR---------KKPMPADVIPEASRGGDKLNELKSELRSKA 630
            |......|.:|...:.::..::...|         ....||.:.....| |:|...::...|| .
  Fly   255 MTQQHQSAYLLNPSVSVLTVKQVNFRHAGNYTCAPSNARPASITVHVLR-GEKTAAMQHANRS-I 317

  Fly   631 YDVEYSEAGGDGLAINLTQSPMPDVQMKG--ATLGVPLAGPVKFDERFSGDF 680
            .|.|.:..|..||           :.:.|  .|.||.|||.:.:   |||.|
  Fly   318 LDTETNGNGTFGL-----------ITLGGLNGTSGVTLAGGILY---FSGLF 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845
		IG_like	88..182	CDD:214653
		C2-set_2	189..279	CDD:285423
		Ig_2	307..379	CDD:290606	4/11 (36%)
		I-set	382..462	CDD:254352	22/118 (19%)
		IGc2	396..446	CDD:197706	16/83 (19%)
		Ig	466..561	CDD:299845	17/106 (16%)
		IG_like	478..561	CDD:214653	17/94 (18%)
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	18/76 (24%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	15/69 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810