DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and dpr3

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	67/347 - (19%)
Similarity:	120/347 - (34%)	Gaps:	121/347 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SSQSSHHGDSSSSSSSSSSSSGSSSAAAS--------------------------SANDESKPKG 76
            ||||......::|:|:||.||.||.|.|.                          :..|..:.:.
  Fly   155 SSQSQSPSPPAASASASSPSSFSSFAVAHGPQTEATNHTFKSLAFLDASFGSDLFAQTDAKRERS 219

  Fly    77 G--DNGGQ-----------HFAMEPQDQTAVVG-SRVTLPCRV-----------------MEKVG 110
            |  |...|           .|.| |::.|...| :...:.|||                 :..||
  Fly   220 GAADEESQDADTSQSLPIFDFGM-PRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVG 283

  Fly   111 ALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIR- 174
            ...:|.|             :|:.:..|.:..:::|.:...:..|...|:|||...|:.....:
  Fly   284 TATYTSD-------------KRFQVTESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMSMAFQL 335

  Fly   175 -----SRFAKLTVLVPP----------------EAPKIT--------QGDYLVT---TEDREIEL 207
                 |..||..:..||                :.|.:.        :|::::|   .:|.:.|:
  Fly   336 NIIEISPDAKAVISGPPDLHFKAGSAIILNCLVQQPSVKDIGPIYWYRGEHMITPFDADDGQPEI 400

  Fly   208 ECVSQGGKPAA--EITWIDGLGNVLTKGIEY-----VKEPLADSRRITARSILKLAPKKEHHNTT 265
            . ..:|..|..  |.|..:.:.:.:...:|:     ::..|.|    |.:|.|:::..:......
  Fly   401 P-AGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQLGD----TLKSRLRISNAQTTDTGN 460

  Fly   266 FTCQAQNTADRTYRSAKLLLEV 287
            :|||     ..|..||.:|:.|
  Fly   461 YTCQ-----PTTASSASVLVHV 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	22/119 (18%)
		IG_like	88..182	CDD:214653	22/117 (19%)
		C2-set_2	189..279	CDD:285423	19/107 (18%)
		Ig_2	307..379	CDD:290606
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	19/99 (19%)
		IG_like	243..329	CDD:214653	19/98 (19%)
		Ig	350..464	CDD:299845	18/118 (15%)
		IG_like	<441..477	CDD:214653	11/44 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810