DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and DIP-kappa

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	104/393 - (26%)
Similarity:	153/393 - (38%)	Gaps:	64/393 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 DNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVG-ALQWTKDDFG--LGQHRN-LSGFERYSMVGS 138
            |:....||....:.|..||....:.|.|....| .:.|.:.|..  |..|.| :|...|.|:..:
  Fly    70 DSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYN 134

  Fly   139 DEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPK-ITQGDYLVTTED 202
            |.. .:.|.|..:...|...|.|||...|     :|||...|.|:|||...: :|..| :|..|.
  Fly   135 DHR-SWYLHIKEVEETDRGWYMCQVNTDP-----MRSRKGYLQVVVPPIIVEGLTSND-MVVREG 192

  Fly   203 REIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFT 267
            :.|.|.|.:: |.|...:.|....|..:..|.|:|.  :.|...:....:.:|      |...:.
  Fly   193 QNISLVCKAR-GYPEPYVMWRREDGEEMLIGGEHVN--VVDGELLHITKVSRL------HMAAYL 248

  Fly   268 CQAQNTADRTYRSAKLLLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFI 332
            |.|.|....:. |.::.|.|::.|.:.:.   ..|.|..:  |.:|||.|..:|.|..::| |..
  Fly   249 CVASNGVPPSI-SKRVHLRVQFPPMLSIP---NQLEGAYL--GQDVILECHTEAYPASINY-WTT 306

  Fly   333 NDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDI-SFGPVFRQRPVSVEADLG 396
            .    .||    |||.:.||    |..|.|..:.|....:..||.| :.||          .|.|
  Fly   307 E----RGD----MIISDTSR----AGDKYETTSTVSGYTKYMKLKIRAVGP----------NDFG 349

  Fly   397 ATVSMRCDVAGNPEPEIEW---ISENSDQVVGVAAELKLKVSSETAGR----YFCKAVVNGFPEI 454
               :.|| ||.|...|.:.   :.|.......:.:|:.|...|....|    .|..|  |..|:.
  Fly   350 ---TYRC-VAKNSLGETDGNIKLDEMPTPTTAIISEMSLLNRSYDGKRRHRNKFDSA--NALPDY 408

  Fly   455 GAE 457
            |.|
  Fly   409 GVE 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	27/99 (27%)
		IG_like	88..182	CDD:214653	27/97 (28%)
		C2-set_2	189..279	CDD:285423	20/90 (22%)
		Ig_2	307..379	CDD:290606	23/72 (32%)
		I-set	382..462	CDD:254352	20/83 (24%)
		IGc2	396..446	CDD:197706	13/56 (23%)
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	27/97 (28%)
		IG_like	82..174	CDD:214653	28/97 (29%)
		IG_like	184..267	CDD:214653	21/93 (23%)
		IGc2	191..255	CDD:197706	17/72 (24%)
		IG_like	282..368	CDD:214653	33/114 (29%)
		Ig	288..367	CDD:143165	32/105 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810