DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kirre and Dscaml1

DIOPT Version :9

Sequence 1:NP_001245505.1 Gene:kirre / 31292 FlyBaseID:FBgn0028369 Length:956 Species:Drosophila melanogaster
Sequence 2:NP_001101611.1 Gene:Dscaml1 / 315615 RGDID:1304887 Length:2111 Species:Rattus norvegicus


Alignment Length:540 Identity:125/540 - (23%)
Similarity:197/540 - (36%) Gaps:93/540 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 SSSSGSSSAAASSAND--ESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVM-EKVGALQWTK 116
            |..:..|:.|..|..|  ||.|...|  |.|      .|....|..|.|||... ..:.|::|.|
  Rat   263 SGETRQSNGARLSVTDPAESIPTILD--GFH------SQEVWTGHAVELPCAASGYPIPAIRWLK 319

  Fly   117 DDFGLGQHRNLSGFERYS--MVGSDEEGDFSLDIYPLMLDDDAKYQCQVGP--GPQGEQGIRSRF 177
            |.      |.|....|::  :.|        |.|..|..:|...|.|:|..  |.....|:.:..
  Rat   320 DG------RPLPADSRWAKRITG--------LTISDLRTEDSGTYICEVTNTFGSAEANGVLTVI 370

  Fly   178 AKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLA 242
            ..|.|.:.|:..|...|..::        |.| :..|.|...|.|.        :..|.|....|
  Rat   371 DPLHVTLTPKKLKTGIGSTVI--------LSC-ALTGSPEFTIRWY--------RNTELVLPGEA 418

  Fly   243 DSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVGGALAGGKI 307
            .|.|..:...|.::..::.|:..:.|.|...|......|.::|| ...|:::.|     .:...:
  Rat   419 ISIRGLSNETLLISSAQKSHSGAYQCFATRKAQTAQDFAIIVLE-DGTPRIVSS-----FSEKVV 477

  Fly   308 PEGAEVILSCQADANPHELSYRWFINDELMT------------GDFTTKMIIHNVSRQYHD-AIV 359
            ..|.:..|.|.|...|.. :..|.::||.:.            .|.||...::....|..| .:.
  Rat   478 NPGEQFSLMCAAKGAPPP-TVTWALDDEPVVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVY 541

  Fly   360 KCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEW------ISE 418
            :|...|:||.:|...::::. ||...:...::.|..|....:.|.|.|.|...|:|      :.:
  Rat   542 RCTARNSVGSAEYQARINVR-GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPD 605

  Fly   419 NSDQVVGVAAELKL----KVSSETAGRYFCKAVVNGFPEIGAEATLYVKRAPIITSHKVQFGGVG 479
            |..|||.....|||    |...|  |.|.|..::.....|.....:.||..|:|...:.....:|
  Rat   606 NHRQVVFENGTLKLTDVQKGMDE--GEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIG 668

  Fly   480 GRVKIDCLAFSIPKAEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKY 544
            ..:.|.|:..|......|.|..:|::|...|.   :.|..:..:     ::|.|......|.|.|
  Rat   669 QLLYIPCVVSSGDMPIRITWRKDGQVIISGSG---VTIESKEFM-----SSLQISSVSLKHNGNY 725

  Fly   545 NCTVMNSYGGDSLVITLLRE 564
            .|...|:      ..|:.||
  Rat   726 TCIASNA------AATVSRE 739

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kirreNP_001245505.1 Ig 87..183 CDD:299845 24/100 (24%)
IG_like 88..182 CDD:214653 24/98 (24%)
C2-set_2 189..279 CDD:285423 18/89 (20%)
Ig_2 307..379 CDD:290606 18/84 (21%)
I-set 382..462 CDD:254352 22/89 (25%)
IGc2 396..446 CDD:197706 19/59 (32%)
Ig 466..561 CDD:299845 19/94 (20%)
IG_like 478..561 CDD:214653 17/82 (21%)
Dscaml1NP_001101611.1 IG 101..173 CDD:214652
IGc2 101..168 CDD:197706
Ig 183..276 CDD:299845 3/12 (25%)
IG_like 195..276 CDD:214653 3/12 (25%)
I-set 291..369 CDD:254352 24/97 (25%)
IGc2 298..359 CDD:197706 20/74 (27%)
IGc2 386..447 CDD:197706 15/77 (19%)
I-set 466..560 CDD:254352 20/99 (20%)
Ig 466..556 CDD:299845 20/95 (21%)
IGc2 577..635 CDD:197706 19/59 (32%)
IG_like 665..744 CDD:214653 20/89 (22%)
Ig 673..739 CDD:143165 17/79 (22%)
I-set 748..843 CDD:254352
Ig7_DSCAM 765..843 CDD:143211
I-set 849..942 CDD:254352
Ig 861..949 CDD:299845
FN3 945..1039 CDD:238020
FN3 1046..1143 CDD:238020
fn3 1151..1237 CDD:278470
FN3 1249..1340 CDD:238020
IGc2 1364..1428 CDD:197706
FN3 1442..1532 CDD:238020
FN3 1546..1618 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.