DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and dpr7

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_001096850.2	Gene:	dpr7 / 2768865	FlyBaseID:	FBgn0053481	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	63/301 - (20%)
Similarity:	99/301 - (32%)	Gaps:	95/301 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MRSSRLLVLP-LILVLILTLLLQPIAVHAKSKKNKSSQSSHHGDSSSSSSSSSSSSGSSSAAASS 67
            :.:|.:.:.| :||||.|.:..|.|                              |.:|..:.:.
  Fly    10 LNNSPIKIKPFIILVLNLNIWCQYI------------------------------SATSYLSLND 44

  Fly    68 ANDESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVG-ALQWTKDDFGLGQHRNL---- 127
            ..:..:|...|       :.|::.:|||.....|.|||..|.. .:.|.:       .|:|
  Fly    45 LTNLERPFFDD-------ISPRNVSAVVDEIAILRCRVKNKGNRTVSWMR-------KRDLHILT 95

  Fly   128 ------SGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGI------------- 173
                  :|.:|:|::......|:.|.|......|...|:|||...|:....|
  Fly    96 TNIYTYTGDQRFSVIHPPGSEDWDLKIDYAQPRDSGVYECQVNTEPKINLAICLQVIADNDFQDL 160

  Fly   174 --RSRFAKLTVLVPPEAPKITQGDYLVTTE-----DREIELECVSQGGKPAAEITWIDGLGNV-- 229
              :.||..         .|..:...|.:||     |..|.|.|......|:  :.|..|...|
  Fly   161 KTKKRFYD---------TKSARAKILGSTEIHVKRDSTIALACSVNIHAPS--VIWYHGSSVVDF 214

  Fly   230 --LTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTC 268
              |..||....|  ......|:|.:|..|..::..|  :||
  Fly   215 DSLRGGISLETE--KTDVGTTSRLMLTRASLRDSGN--YTC 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	27/121 (22%)
		IG_like	88..182	CDD:214653	27/119 (23%)
		C2-set_2	189..279	CDD:285423	23/89 (26%)
		Ig_2	307..379	CDD:290606
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
dpr7	NP_001096850.2	V-set	56..145	CDD:284989	24/95 (25%)
		IG_like	58..140	CDD:214653	23/88 (26%)
		IG_like	179..265	CDD:214653	21/79 (27%)
		Ig	187..257	CDD:299845	19/71 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910