DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and dpr9

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_001287332.1	Gene:	dpr9 / 2768670	FlyBaseID:	FBgn0038282	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	74/349 - (21%)
Similarity:	109/349 - (31%)	Gaps:	128/349 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 SSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAME-PQDQTAVVGSRVTLPCR 104
            ||.|..||:||::.||...|.....|...:|::     |.|.:|... .::.||::|....|.||
  Fly   220 SSLHKASSASSNTFSSQLASGFHRNSIDLEEAR-----NAGPYFDKAFSKNVTALLGKTAYLNCR 279

  Fly   105 VM---EKVGALQ--WTKDDFGLGQHRNL----------SGFERYSMVGSDEEGDFSLDI-YPLML 153
            |.   .|...||  |.:       ||::          :..:|:..:...:..|:.|.| || ..
  Fly   280 VKNLGNKTMLLQVSWVR-------HRDIHLLTVGRYTYTSDQRFRAIHQPQTEDWMLQIKYP-QH 336

  Fly   154 DDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGG-KPA 217
            .|...|:|||...|.     .|.:..|.|:.|  :.:|.....|.......|.|.|:.|.. :|.
  Fly   337 RDSGIYECQVSTTPH-----MSHYIHLNVVEP--STEIIGAPDLYIESGSTINLTCIIQNSPEPP 394

  Fly   218 AEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAK 282
            |.|.|                                      :||..|....|
  Fly   395 AYIFW--------------------------------------NHNNAFPSHPQ----------- 410

  Fly   283 LLLEVKY-APKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFINDELMTGDFTTKMI 346
               .:.| :|:..||||..                                     .||.||..:
  Fly   411 ---IINYDSPRGGVSVVTN-------------------------------------KGDTTTSFL 435

  Fly   347 IHNVSRQYHDAIVKCEVVNAVGKS 370
            :...:|.......:|...||..||
  Fly   436 LIKSARPSDSGHYQCNPSNAKPKS 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	27/112 (24%)
		IG_like	88..182	CDD:214653	27/109 (25%)
		C2-set_2	189..279	CDD:285423	14/90 (16%)
		Ig_2	307..379	CDD:290606	10/64 (16%)
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
dpr9	NP_001287332.1	Ig	263..361	CDD:299845	27/110 (25%)
		IG_like	263..360	CDD:214653	27/109 (25%)
		IG_like	371..464	CDD:214653	29/178 (16%)
		IGc2	377..456	CDD:197706	25/167 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810