Protein Alignment kirre and syg-2

DIOPT Version :9

• Sequence 1: NP_001245505.1
• Gene: kirre / 31292
• FlyBaseID: FBgn0028369
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001309674.1
• Gene: syg-2 / 181561
• WormBaseID: WBGene00007750
• Length: 1230
• Species: Caenorhabditis elegans
• Alignment Length: 993
• Identity: 187/993 - (18%)
• Similarity: 318/993 - (32%)
• Gaps: 320/993 - (32%)

  Fly    50 SSSSSSSSSGSSSAAASSANDE---SKPKGGDNGGQHF--AMEP---------QDQTAVVGSRVT 100
            |||:.|..|...|..|...|.|   :.|: |.:..||.  .:.|         :|:....|..|.
 Worm   388 SSSNVSVHSNELSVEAHQINVECMATNPE-GSSAKQHVIKIIAPPKAPIITGLEDRKFFEGDIVN 451

  Fly   101 LPC--------------RVMEK-----VGALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSL 146
            :.|              |..||     ...::|::.:   |.|..::||..||.:.
 Worm   452 VTCEAQGGNPLAELSWYRGSEKHLVKGRKKMKWSQVN---GAHNEVAGFSSYSTLA--------- 504

  Fly   147 DIYPLMLD---DDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGD-----YLVTTEDR 203
                |.:|   :..:.:|:.......|..|.|::  |:|..||....|...|     .||   .:
 Worm   505 ----LRVDRTMNTQRLKCEATNAALDEPLIESQY--LSVYYPPRRVLIRPADSGDQRLLV---GK 560

  Fly   204 EIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLAD-SRRITAR-------SILKLAPKKE 260
            ...|.|.:....|||.|:|      ..::..:..|..|.| |...|.|       ::|...|.:|
 Worm   561 SARLVCGTLSSNPAAHISW------QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEE 619

  Fly   261 HHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVI----VSVVGGALAGGKIPEGAEVILSCQADA 321
            :..|...|.|.:...:...:....|.|.|.||::    |:||        :.||.....:.....
 Worm   620 YDGTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVV--------MSEGDSFKENLTVRG 676

  Fly   322 NPHELSYRWFIN----DELMTGDFTTKMIIHNVSRQYHDA-IVKCEVVNAVGKSEQSKKLDISFG 381
            ||....::|..|    |..:...|....::........|| :......|:||.:..:.||.:.:.
 Worm   677 NPAISLWQWRKNGVPFDHTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAVEYS 741

  Fly   382 PVFRQRPVSVEADLGATVSMRCDVAGNPEPE--IEWISENSDQVVG-----VAAELKLKVSSETA 439
            .........|.|..|.||.:.|:..|.|...  |.|. :|.:.:..     ..|.|:|..:.:.:
 Worm   742 ARITSISTPVIAATGDTVLLECEADGEPSKANMIHWY-KNGEILAAQHRGHKKAILRLNATEQQS 805

  Fly   440 GRYFCKA--------------VVNGFPEIGAEATLYVKRAPIITSHKVQFGGVGGRVKIDCLAFS 490
            |.|.|||              :||..|.: .....|.|.|.|:          ||..|..|..::
 Worm   806 GEYTCKADNGIGVPAEGQTFLLVNSAPRV-LPVARYAKTAGIL----------GGVAKARCKVYA 859

  Fly   491 IPKAEHILWSFEGKIINMSSA---------DPDIY---IFEEHHLPEGVRAALIIRDSKATHFGK 543
            :|..|.: |..:.::|..:|:         |...|   ::.::.:|:             .:..|
 Worm   860 VPTVEFV-WEKDEQLIKKNSSKYSIVNTQIDYSTYESTLWIKNIVPD-------------DYTKK 910

  Fly   544 YNCTVMNSYGGDSLVITLL-----REPGNIPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKP 603
            ..|...||:|.|.|.|.::     .||.|:.:....:.:            |.:.:.
 Worm   911 VKCIARNSFGTDHLSIPIIPPTHPDEPFNLTMTNSTLNT------------ISVAWE-------- 955

  Fly   604 MPADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGDGL-AINLTQSPMPDVQMKGATLGVPLA 667
                  |....|.|::           ::|:|.....|.: .:|.|.:.:
 Worm   956 ------PRFDGGSDQI-----------FEVKYRRQNDDLIHLVNTTHTNL--------------- 988

  Fly   668 GPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQANGYAHYFEYALDYSPPGGEGAAVV 732
                   |.||....:.|..|..              |..|.|:|..:...:.::....:|.
 Worm   989 -------RLSGLATANTYFFQIR--------------SINARGFASSWTSPVIFATLNEDGV--- 1029

  Fly   733 VGSGGVGKLKNGGMNSAT-LPH---------------------------------SAAATVNGGG 763
                .|..::|..:...| :|:                                 .|...:|||.
 Worm  1030 ----NVAMIRNEKLKLTTWIPYILIFIVLFMLLNVVICCFVCNRTKKRKLREKTEMARTAINGGD 1090

  Fly   764 A----------GNGGGASLPRNQRHEIQQSQQS---------NGFLGQP----------LLQNGI 799
            .          ||.|.:....:.|.|:.:.:.|         ||:: ||          ||:...
 Worm  1091 VRQVQMYGTMMGNDGMSRRDIDDRPEMSEDEHSVRTMIEVSPNGYM-QPIEPMLYESTGLLEYDY 1154

  Fly   800 DSRFSAIYGNPYLRTNSSLLPPLPPPSTANPAATPAPPPYHAARHGHAHHANGG------LKHFV 858
            .:|   .|......|.|.....:|.|.       |..|.||:..:.....:|..      |..|:
 Worm  1155 QTR---SYMGSSQGTRSMTYANVPYPE-------PPQPSYHSNWNSLQRQSNNNTSPQHHLSTFI 1209

  Fly   859 GGAV-ITTSPVGNVNING 875
            ...: :...|:....::|
 Worm  1210 NPNMGVRAGPINYAQLDG 1227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	22/126 (17%)
		IG_like	88..182	CDD:214653	22/124 (18%)
		C2-set_2	189..279	CDD:285423	23/102 (23%)
		Ig_2	307..379	CDD:290606	15/76 (20%)
		I-set	382..462	CDD:254352	22/100 (22%)
		IGc2	396..446	CDD:197706	15/56 (27%)
		Ig	466..561	CDD:299845	21/106 (20%)
		IG_like	478..561	CDD:214653	20/94 (21%)
syg-2	NP_001309674.1	IG_like	25..105	CDD:214653
		Ig	33..122	CDD:299845
		Ig	147..228	CDD:299845
		IGc2	248..313	CDD:197706
		Ig	450..537	CDD:299845	19/104 (18%)
		Ig	559..632	CDD:299845	19/78 (24%)
		I-set	657..738	CDD:254352	18/88 (20%)
		Ig	665..738	CDD:299845	14/72 (19%)
		IG_like	748..828	CDD:214653	19/80 (24%)
		IGc2	756..817	CDD:197706	17/61 (28%)
		Ig	845..922	CDD:299845	18/100 (18%)
		FN3	934..1023	CDD:238020	21/161 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I8442
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141865at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920