DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and zig-4

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	49/226 - (21%)
Similarity:	86/226 - (38%)	Gaps:	60/226 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 AKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITW------IDGLG--NVLTKGI 234
            ||:.::.|.|:..|..|      |..::..:.:|   .|||.|.|      |.|..  ||..|.:
Worm    44 AKIKIVAPLESALIPGG------ETYQLRCDIMS---TPAATIHWKFNGKLIQGSNELNVEEKLL 99

  Fly   235 EYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEV------------ 287
            .:.| .:.|:..:.  |||.:......::.|::|...|    .:::.:.:.||
Worm   100 NFGK-AIVDTGIVA--SILTIQCPSAENSGTYSCVGYN----GHQTIETVAEVEIEGEASGCRSN 157

  Fly   288 -KYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFINDELM----------TGDF 341
             |.||:::..........|.:     ..|.|:|:   .::.:.|..||||:          .||.
Worm   158 HKSAPEIVFWTDSRFEMTGNV-----ATLVCRAN---QQVDWVWMSNDELVKNNDKFTVLSNGDL 214

  Fly   342 TTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQ 372
            ..|.|:.:....|     .|...|..|::.|
Worm   215 VIKNIVWDDMGTY-----TCIARNQFGEARQ 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845	2/4 (50%)
		IG_like	88..182	CDD:214653	2/3 (67%)
		C2-set_2	189..279	CDD:285423	22/97 (23%)
		Ig_2	307..379	CDD:290606	17/76 (22%)
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
zig-4	NP_509335.1	I-set	47..147	CDD:254352	26/115 (23%)
		Ig	65..144	CDD:143165	19/88 (22%)
		IG_like	176..245	CDD:214653	18/78 (23%)
		Ig	<193..238	CDD:299845	13/49 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900