DRSC/TRiP Functional Genomics Resources

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Protein Alignment kirre and Dscam

DIOPT Version :9

Sequence 1:NP_001245505.1 Gene:kirre / 31292 FlyBaseID:FBgn0028369 Length:956 Species:Drosophila melanogaster
Sequence 2:XP_038943864.1 Gene:Dscam / 171119 RGDID:619992 Length:2034 Species:Rattus norvegicus


Alignment Length:686 Identity:141/686 - (20%)
Similarity:230/686 - (33%) Gaps:202/686 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 PIAVHAKSKKNKSS---QSSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAME 87
            |:.:..:.:|..:.   ::|...||.|.....|:..|::...                |:.:..:
  Rat   264 PLELSGRFQKTVTGLLIENSRPSDSGSYVCEVSNRYGTAKVI----------------GRLYVKQ 312

  Fly    88 PQDQT-------AVVGSRVTLPCRVM-EKVGALQWTKDD--FGLGQHRNLSGFERYSMVGSDEEG 142
            |...|       :.|||:|:|.|.|. .:...|.|.::.  ...|::..::|....:::      
  Rat   313 PLKATISPRKVKSSVGSQVSLSCSVTGNEDQELSWYRNGEILNPGKNVRITGLNHANLI------ 371

  Fly   143 DFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQG-DYLVTTEDREIE 206
               :|  .::..|...|||.|.......|..      :.|::....|||... ...|.:....:.
  Rat   372 ---MD--HMVKSDGGAYQCFVRKDKLSAQDY------VQVVLEDGTPKIISAFSEKVVSPAEPVS 425

  Fly   207 LECVSQGGKPAAEITW-------IDGLGNVLTKGIEYVKEPLADSRRITAR----SILKLAPKKE 260
            |.| :..|.|...:||       :.|.|:.:             |:.||:.    |.|.::..:.
  Rat   426 LVC-NVKGTPLPTVTWTLDDDPILKGSGHRI-------------SQMITSEGNVVSYLNISSSQV 476

  Fly   261 HHNTTFTCQAQNTAD--------------------------------------------RTYRSA 281
            .....:.|.|.|:|.                                            :.|::|
  Rat   477 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNA 541

  Fly   282 KLLL------------------------EVKYAPKVIV----SVVGGALAGGKIPE--------- 309
            .||.                        |.:|...|:|    |.........|:|.         
  Rat   542 NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 606

  Fly   310 ---GAEVILSC-------------QADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAI 358
               |..|.:.|             |.|..|...|....|::.    |||:.:.|.|:|.. |:..
  Rat   607 FSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNI----DFTSSLRISNLSLM-HNGN 666

  Fly   359 VKCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEW-------- 415
            ..|...|.....|...:|.:...|.|..:|...:...|..|.:.|...|.|.|.|.|        
  Rat   667 YTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGV 731

  Fly   416 -----ISENSD-QVVGVAAELKLKVSSETAGRYFCKAVVNGFPEIGAEAT----LYVKRAPIITS 470
                 |:.|.. ||:...:.|...|..|.:|.|.|| |.|   ::||:.:    |.||...:|||
  Rat   732 PQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCK-VSN---DVGADVSKSMYLTVKIPAMITS 792

  Fly   471 H-KVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIR 534
            : .......|.|.::.|.|.. .|...:.|..|.:|||...|.   |:.....:.|.|.:.|.|.
  Rat   793 YPNTTLATQGQRKEMSCTAHG-EKPIIVRWEKEDRIINPEMAR---YLVSTKEVGEEVISTLQIL 853

  Fly   535 DSKATHFGKYNCTVMNSYGGDSLVITL-LREPGNIP 569
            .:.....|.::|..:||||.|..:|.| ::||.:.|
  Rat   854 PTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP 889

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kirreNP_001245505.1 Ig 87..183 CDD:299845 20/105 (19%)
IG_like 88..182 CDD:214653 20/103 (19%)
C2-set_2 189..279 CDD:285423 21/145 (14%)
Ig_2 307..379 CDD:290606 20/96 (21%)
I-set 382..462 CDD:254352 27/97 (28%)
IGc2 396..446 CDD:197706 18/63 (29%)
Ig 466..561 CDD:299845 27/95 (28%)
IG_like 478..561 CDD:214653 24/82 (29%)
DscamXP_038943864.1 Ig 26..121 CDD:416386
Ig strand A' 33..37 CDD:409353
Ig strand B 40..49 CDD:409353
Ig strand C 55..61 CDD:409353
Ig strand C' 63..66 CDD:409353
Ig strand D 72..75 CDD:409353
Ig strand E 80..85 CDD:409353
Ig strand F 98..106 CDD:409353
Ig strand G 109..121 CDD:409353
Ig 125..210 CDD:416386
Ig strand A 126..130 CDD:409353
Ig strand A' 132..136 CDD:409353
Ig strand B 139..149 CDD:409353
Ig strand C 157..163 CDD:409353
Ig strand C' 164..167 CDD:409353
Ig strand E 179..185 CDD:409353
Ig strand F 191..201 CDD:409353
IGc2 239..300 CDD:197706 7/35 (20%)
Ig strand B 242..246 CDD:409353
Ig strand C 255..259 CDD:409353
Ig strand F 290..295 CDD:409353 1/4 (25%)
Ig 313..395 CDD:416386 19/92 (21%)
Ig strand A 314..319 CDD:409353 1/4 (25%)
Ig strand A' 322..326 CDD:409353 0/3 (0%)
Ig strand B 329..339 CDD:409353 5/9 (56%)
Ig strand C 344..350 CDD:409353 2/5 (40%)
Ig strand C' 351..354 CDD:409353 0/2 (0%)
Ig strand E 368..374 CDD:409353 1/16 (6%)
Ig strand F 381..389 CDD:409353 4/7 (57%)
Ig 406..501 CDD:416386 21/108 (19%)
Ig strand A 406..409 CDD:409353 1/2 (50%)
Ig strand A' 415..419 CDD:409353 1/3 (33%)
Ig strand B 422..431 CDD:409353 2/9 (22%)
Ig strand C 436..442 CDD:409353 2/5 (40%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 452..460 CDD:409353 2/20 (10%)
Ig strand E 464..473 CDD:409353 2/8 (25%)
Ig strand F 480..488 CDD:409353 2/7 (29%)
Ig strand G 491..501 CDD:409353 0/9 (0%)
Ig 504..593 CDD:416386 9/88 (10%)
Ig strand A 505..507 CDD:409353 0/1 (0%)
Ig strand A' 512..516 CDD:409353 0/3 (0%)
Ig strand B 519..526 CDD:409353 0/6 (0%)
Ig strand C 533..539 CDD:409353 0/5 (0%)
Ig strand C' 540..542 CDD:409353 0/1 (0%)
Ig strand D 549..553 CDD:409353 0/3 (0%)
Ig strand E 557..563 CDD:409353 0/5 (0%)
Ig strand F 571..579 CDD:409353 2/7 (29%)
Ig strand G 583..593 CDD:409353 1/9 (11%)
Ig 596..686 CDD:416386 20/94 (21%)
Ig strand A 597..599 CDD:409353 0/1 (0%)
Ig strand B 611..620 CDD:409353 2/8 (25%)
Ig strand C 625..632 CDD:409353 0/6 (0%)
Ig strand C' 634..636 CDD:409353 0/1 (0%)
Ig strand D 643..648 CDD:409353 1/4 (25%)
Ig strand E 651..658 CDD:409353 2/6 (33%)
Ig strand F 665..673 CDD:409353 1/7 (14%)
Ig strand G 676..685 CDD:409353 1/8 (13%)
Ig_DSCAM 689..784 CDD:409397 27/98 (28%)
Ig strand B 707..711 CDD:409397 1/3 (33%)
Ig strand C 720..724 CDD:409397 1/3 (33%)
Ig strand E 749..753 CDD:409397 0/3 (0%)
Ig strand F 763..768 CDD:409397 3/5 (60%)
Ig strand G 777..780 CDD:409397 0/2 (0%)
Ig_DSCAM 785..884 CDD:409398 29/102 (28%)
Ig strand B 805..809 CDD:409398 0/3 (0%)
Ig strand C 818..822 CDD:409398 0/3 (0%)
Ig strand E 848..852 CDD:409398 1/3 (33%)
Ig strand F 862..867 CDD:409398 1/4 (25%)
Ig strand G 875..878 CDD:409398 0/2 (0%)
FN3 885..978 CDD:238020 2/5 (40%)
FN3 986..1083 CDD:238020
FN3 1091..1184 CDD:238020
FN3 1189..1278 CDD:238020
Ig_3 1287..1363 CDD:404760
Ig strand B 1303..1307 CDD:409353
Ig strand C 1316..1320 CDD:409353
Ig strand E 1342..1346 CDD:409353
Ig strand F 1356..1361 CDD:409353
FN3 1380..1470 CDD:238020
FN3 1486..1555 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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