DRSC/TRiP Functional Genomics Resources

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Protein Alignment kirre and Papln

DIOPT Version :9

Sequence 1:NP_001245505.1 Gene:kirre / 31292 FlyBaseID:FBgn0028369 Length:956 Species:Drosophila melanogaster
Sequence 2:NP_001192272.1 Gene:Papln / 170721 MGIID:2386139 Length:1302 Species:Mus musculus


Alignment Length:277 Identity:65/277 - (23%)
Similarity:97/277 - (35%) Gaps:98/277 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   382 PVFRQR-----PVSVEADLGATVSMRCDVAGNPEPEIE--W------ISENSDQVVGVAAELKLK 433
            |.:|.|     |..|:|..|..|.:.|  .||...|.:  |      ||.|..|:....:.:..:
Mouse   922 PSYRIRLAGSEPSLVQAAPGQAVQLFC--PGNIPSEFQAGWQKEGRPISSNRYQLQADGSLIISR 984

  Fly   434 VSSETAGRYFCKA-------------VVNG------------FPE--------------IGAEAT 459
            :..|.||.|.|.:             |..|            |||              .||||.
Mouse   985 LRPEDAGIYSCGSHRPGHEPQEIQLRVTGGDMAVFPEGQPRHFPEPRNPDLGHGPPHRGTGAEAG 1049

  Fly   460 LYVKRAPIITSH----------KVQFGGV----GGRVKIDCLA--FSIPKAEHILWSFEGKIINM 508
            .:...:|   ||          :.|.|.|    |.|:::.|.|  |.:|..|   |..:|::::.
Mouse  1050 GHRVLSP---SHPRPATRLRLDRTQPGVVDASPGQRIRLTCRAEGFPVPTIE---WQRDGQLVSS 1108

  Fly   509 SSADPDIYIFEEHHL-PEGVRAALIIRDSKATHFGKYNCTVMNSYGGDS--LVITLLRE---PGN 567
                      ..|.: |:|   :|:|........|.|:|...|....|.  :.:.:|||   .|.
Mouse  1109 ----------PRHQVQPDG---SLVISRVDVEDGGYYSCVAFNGQDRDQRWVQLRVLRELTITGL 1160

  Fly   568 IPVLLVVMGS---MFCV 581
            .|.:.|..|.   :.||
Mouse  1161 PPAVTVAEGDTARLLCV 1177

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kirreNP_001245505.1 Ig 87..183 CDD:299845
IG_like 88..182 CDD:214653
C2-set_2 189..279 CDD:285423
Ig_2 307..379 CDD:290606
I-set 382..462 CDD:254352 31/131 (24%)
IGc2 396..446 CDD:197706 16/57 (28%)
Ig 466..561 CDD:299845 25/113 (22%)
IG_like 478..561 CDD:214653 20/91 (22%)
PaplnNP_001192272.1 TSP1 30..81 CDD:214559
ADAM_spacer1 184..299 CDD:368694
TSP1 309..362 CDD:214559
TSP1 389..447 CDD:214559
TSP1 447..504 CDD:214559
TSP1 511..562 CDD:214559
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 563..648
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 694..737
Kunitz_BPTI 771..822 CDD:333766
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 822..924 1/1 (100%)
Papilin_u7 831..922 CDD:374683 65/277 (23%)
Ig 932..>995 CDD:386229 18/64 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1024..1064 10/42 (24%)
I-set 1070..1141 CDD:369462 21/86 (24%)
Ig 1157..1241 CDD:386229 6/21 (29%)
PLAC 1257..1289 CDD:370061
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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