DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kirre and LOC110439986

DIOPT Version :9

Sequence 1:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	XP_021333824.1	Gene:	LOC110439986 / 110439986	-ID:	-	Length:	358	Species:	Danio rerio

Alignment Length:	393	Identity:	105/393 - (26%)
Similarity:	155/393 - (39%)	Gaps:	92/393 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 PEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITAR 250
            |:.|.|:.....|..|...:.|.|.|....||...:|..|             |....|.||.
Zfish    19 PDTPVISINRSAVIKEGDSVTLNCSSNANPPALNFSWFKG-------------ETFVGSSRIF-- 68

  Fly   251 SILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPK-VIVSVVGGALAGGKIPEGAEVI 314
            :|.|::   ...|..:.|:|:|.....| |..:.|:|:|.|: :.||:...|:    |..|..|.
Zfish    69 NISKIS---SDDNKKYKCKAKNDLGEKY-SDPVTLDVQYPPRNISVSMNRSAV----IMSGDSVT 125

  Fly   315 LSCQADAN-PHELSYRWFINDELMTGD---FTTKMIIHNVSRQYHDAIVKCEVVNAVG-KSEQSK 374
            |||.:|:| |.|:|  |: ..|...|.   |....|..:.|.:|     ||...|..| |.....
Zfish   126 LSCSSDSNPPAEIS--WY-KGETSVGSGRIFNISKISSDDSGEY-----KCRARNDHGEKYSDPV 182

  Fly   375 KLDISFGP----VFRQRPVSVEADLGATVSMRCDVAGNPEPEIEWI----SENSDQVVGVAAELK 431
            .||:.:.|    :..:..|.:|.|   :|::.|....||.....|.    |.||.::..::
Zfish   183 TLDVQYAPDTPVISNRSAVIMEGD---SVTLNCSSNSNPPANFSWFKGNKSLNSGRIFSIS---- 240

  Fly   432 LKVSSETAGRYFCKA-VVNGFPEIGAEATLYVKRAPIITSHKVQFGGV---GGRVKIDCLAFSIP 492
             |:||:.:|.|.|:| .|:| .:.....||.|:..|...|..:....|   |..|.:.|.:.|.|
Zfish   241 -KISSDDSGEYKCRARNVHG-EKYSDPVTLDVQYPPRNISVSMNRSAVIMSGDSVTLSCSSDSNP 303

  Fly   493 KAEHILWSFE-------GKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMN 550
            .|| |.| |:       |:|.|:|....|                    ||     |:|.|...|
Zfish   304 PAE-INW-FKGETSVRSGRIFNISKISSD--------------------DS-----GEYKCRYKN 341

  Fly   551 SYG 553
            .:|
Zfish   342 IHG 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kirre	NP_001245505.1	Ig	87..183	CDD:299845
		IG_like	88..182	CDD:214653
		C2-set_2	189..279	CDD:285423	21/89 (24%)
		Ig_2	307..379	CDD:290606	25/76 (33%)
		I-set	382..462	CDD:254352	23/88 (26%)
		IGc2	396..446	CDD:197706	14/53 (26%)
		Ig	466..561	CDD:299845	25/98 (26%)
		IG_like	478..561	CDD:214653	23/86 (27%)
LOC110439986	XP_021333824.1	Ig_2	22..101	CDD:316418	24/97 (25%)
		Ig_2	115..186	CDD:316418	25/82 (30%)
		Ig_2	193..270	CDD:316418	22/85 (26%)
		Ig_2	284..355	CDD:316418	23/88 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141865at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010