DRSC/TRiP Functional Genomics Resources

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Protein Alignment rst and Kirrel3

DIOPT Version :10

Sequence 1:NP_525058.2 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster
Sequence 2:NP_001420714.1 Gene:Kirrel3 / 67703 MGIID:1914953 Length:803 Species:Mus musculus


Alignment Length:679 Identity:191/679 - (28%)
Similarity:290/679 - (42%) Gaps:129/679 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 FAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDI 94
            |:.:||||..|.|..|||.|.:....|.:.|.||...||..||||.:.:|.:||:...|::.|.|
Mouse    50 FSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKI 114

  Fly    95 YPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVG 159
            ....|.|||.|:||..     |.||||..|.|||||||:.|.|..|.||.......:.:.|.:..
Mouse   115 LRAELQDDAVYECQAI-----QAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADN 174

  Fly   160 GKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTY 224
            .||||.|.|: ..|.|: :...|:...|.|.:|.:..|.|.::|....:..:..|:|.|.|....
Mouse   175 AKPAASIIWL-RKGEVI-NGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGG 237

  Fly   225 RSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSD 289
            :...:.:::::.|.|.::|                       ....::|.:.|...|.|.|||:.
Mouse   238 KETSVTIDIQHPPLVNLSV-----------------------EPQPVLEDNIVTFHCSAKANPAV 279

  Fly   290 VRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQS 354
            .:|||..... ||.....|:....|...:....|.|||.|::|.:..|.|:|:.:.|.....|||
Mouse   280 TQYRWAKRGH-IIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQS 343

  Fly   355 MEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTF-SVSNETAGRYYCKANVPGYAEI 418
            :..|:||....:|....||...|||::..|..|:.....||. ||..|.||:|.|:|.||.....
Mouse   344 LLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAG 408

  Fly   419 SADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSESGHDYSILVD 483
            ..:..:.:.|.|.|.|.:||:.|.|:..:|:||..|.|....::|::....:.|.:...|::...
Mouse   409 EREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETV 473

  Fly   484 AVPGGVKSTL----IIR-DSQAYHYGKYNCTVVNDYGNDVAEIQLQAK----------KSVSLLM 533
            ....||.|||    |:| |.|..    ||||..|.:|:|...|:|:.:          ::.|:.|
Mouse   474 NTEEGVISTLTISNIVRADFQTI----YNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPM 534

  Fly   534 TIVGGISV---VAFLLVLTILVVVYIKC---------------------KKRTKLPPADVISEHQ 574
            .::.|::|   ||||:::..:|..   |                     |.|.:||       .:
Mouse   535 AVIIGVAVGAGVAFLVLMATIVAF---CCARSQRSTGGRPGISGRGTEKKARLRLP-------RR 589

  Fly   575 ITKNGGVSCK---------LEPG------DRTS----------------------------NYSD 596
            ....|.||.|         .||.      |.|:                            .:.:
Mouse   590 ANLKGVVSAKNDIRVEIVHKEPSSGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQN 654

  Fly   597 LKVDISGGYVPYGDYSTHYSPPPQYLTTC 625
            || |.:.||.....:..|:|.|...|::|
Mouse   655 LK-DPTNGYYSVNTFKEHHSTPTISLSSC 682

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rstNP_525058.2 Ig 29..110 CDD:472250 34/79 (43%)
Ig strand B 45..49 CDD:409353 3/3 (100%)
Ig strand E 90..94 CDD:409353 1/3 (33%)
Ig strand F 104..109 CDD:409353 2/4 (50%)
C2-set_2 135..225 CDD:400489 25/89 (28%)
Ig strand B 151..155 CDD:409353 0/3 (0%)
Ig strand C 165..169 CDD:409353 1/3 (33%)
Ig strand E 197..201 CDD:409353 2/3 (67%)
Ig strand F 211..216 CDD:409353 1/4 (25%)
Ig strand G 226..229 CDD:409353 0/2 (0%)
Ig 271..340 CDD:472250 21/68 (31%)
Ig_3 346..411 CDD:464046 24/65 (37%)
Ig 428..524 CDD:472250 33/100 (33%)
Ig strand B 446..450 CDD:409353 1/3 (33%)
Ig strand C 460..464 CDD:409353 0/3 (0%)
Ig strand E 491..495 CDD:409353 3/7 (43%)
Ig strand F 505..510 CDD:409353 3/4 (75%)
Ig strand G 518..521 CDD:409353 0/2 (0%)
Kirrel3NP_001420714.1 IG_like 54..143 CDD:214653 40/93 (43%)
Ig strand B 65..69 CDD:409390 3/3 (100%)
Ig strand C 73..81 CDD:409390 1/7 (14%)
Ig strand E 110..114 CDD:409390 1/3 (33%)
Ig strand F 124..129 CDD:409390 2/4 (50%)
Ig strand G 135..139 CDD:409390 2/3 (67%)
IgI_2_KIRREL3-like 149..246 CDD:409416 25/98 (26%)
Ig strand A 150..153 CDD:409416 1/2 (50%)
Ig strand A' 156..160 CDD:409416 2/3 (67%)
Ig strand B 167..174 CDD:409416 1/6 (17%)
Ig strand C 179..184 CDD:409416 2/4 (50%)
Ig strand C' 187..189 CDD:409416 1/1 (100%)
Ig strand D 192..199 CDD:409416 1/6 (17%)
Ig strand E 206..214 CDD:409416 2/7 (29%)
Ig strand F 223..231 CDD:409416 2/7 (29%)
Ig strand G 237..243 CDD:409416 0/5 (0%)
Ig <267..334 CDD:472250 22/67 (33%)
Ig strand B 267..271 CDD:409437 1/3 (33%)
Ig strand C 280..285 CDD:409437 2/4 (50%)
Ig strand E 304..308 CDD:409437 0/3 (0%)
Ig strand G 326..329 CDD:409437 1/2 (50%)
Ig 335..416 CDD:472250 27/80 (34%)
Ig strand B 352..356 CDD:409549 0/3 (0%)
Ig strand C 365..369 CDD:409549 2/3 (67%)
Ig strand E 381..385 CDD:409549 1/3 (33%)
IgI_5_KIRREL3 418..515 CDD:409479 33/100 (33%)
Ig strand A 419..423 CDD:409479 1/3 (33%)
Ig strand A' 425..428 CDD:409479 0/2 (0%)
Ig strand B 436..443 CDD:409479 3/6 (50%)
Ig strand C 450..455 CDD:409479 1/4 (25%)
Ig strand C' 457..460 CDD:409479 0/2 (0%)
Ig strand D 468..475 CDD:409479 1/6 (17%)
Ig strand E 478..485 CDD:409479 5/6 (83%)
Ig strand F 496..503 CDD:409479 4/10 (40%)
Ig strand G 506..513 CDD:409479 2/6 (33%)

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