DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rst and tmigd1

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001091718.1	Gene:	tmigd1 / 559127	ZFINID:	ZDB-GENE-080303-6	Length:	251	Species:	Danio rerio

Alignment Length:	199	Identity:	44/199 - (22%)
Similarity:	85/199 - (42%)	Gaps:	29/199 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 SVHMSTGSRI---VEHSQVRLECRAD-ANPSDVR-YRWFIN-------DEPIIGGQKTEMVIRNV 314
            |..::.||.:   ||.: |.|.|..| .:||..: .:||.|       :|.::  .::.:.::.|
Zfish    27 SCPLAVGSLLQTAVEET-VTLTCMTDNTDPSSQQELQWFRNGARVKLPEENMM--SRSSLCVQPV 88

  Fly   315 TRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVW 379
            |::...|:..|:::.....:...| .|:||.|......:....:....| |:|||.:||...:||
Zfish    89 TKEDDGAVFTCQLKGDASVNSTVE-FDVSYPPDLNDTIEVFVQETNDAV-LSCEVRANPPVTVVW 151

  Fly   380 IQHPSDRVVGTSTNLTFSVSNETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGD 444
                  :..|...:||......|......:..:|   ::..|.:   :|.....::...||:.|.
Zfish   152 ------KKDGEVLDLTTGSYKSTNNGITAQLTIP---KLKRDVH---QGLYVCETKSAMYGVTGR 204

  Fly   445 TARI 448
            |.::
Zfish   205 TFQV 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653
		Ig	42..114	CDD:299845
		C2-set_2	135..225	CDD:285423
		Ig_3	265..329	CDD:290638	18/75 (24%)
		I-set	346..420	CDD:254352	15/73 (21%)
		Ig	360..425	CDD:299845	15/64 (23%)
		Ig5_KIRREL3-like	428..524	CDD:143235	5/21 (24%)
		IG_like	435..524	CDD:214653	4/14 (29%)
tmigd1	NP_001091718.1	Ig	43..>100	CDD:299845	13/59 (22%)
		IG_like	129..210	CDD:214653	20/93 (22%)
		Ig	135..193	CDD:143165	16/70 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910