DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rst and dpr12

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	60/268 - (22%)
Similarity:	99/268 - (36%)	Gaps:	48/268 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 GKSEDSETLDISYAPSFRQ---RPQSMEADVGSVVSLTCEVDSNPQ-----PEIVWIQHPSDRVV 388
            |.|:....||.|.:|.|..   ...:....:|....|.|:|....:     .:|.||:.....::
  Fly    61 GDSKLDNNLDSSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHIL 125

  Fly   389 GTSTNLTFS---------------------VSNETAGRYYCKANVP-GYAEISADAYVYLKGSPA 431
            .:...|..:                     |.....|.|.|:.:.| |......:..|.:..:..
  Fly   126 SSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFI 190

  Fly   432 IGSQRTQYGLVGDTARIECFASSVPR-ARHVSWTFNGQEIS-SESGHDYSILVDAVPG-GVKSTL 493
            :||......: |.|..:.|.....|. .::|.|..|.:.|: .:|..|  |.::..|| ..:|.|
  Fly   191 LGSGELHVDM-GSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRD--ITIETTPGPRTQSRL 252

  Fly   494 IIRDSQAYHYGKYNCTVVN----------DYGNDVAEIQLQAKKSVSLLMTIVGGISVVAFLLVL 548
            |||:.|....|.|.|:..|          ..|:::|.|..:...|...|..|..  |::|..|:|
  Fly   253 IIREPQVTDSGNYTCSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLTHIFR--SMLAPCLLL 315

  Fly   549 TILVVVYI 556
            ..:||.:|
  Fly   316 NTVVVRHI 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653
		Ig	42..114	CDD:299845
		C2-set_2	135..225	CDD:285423
		Ig_3	265..329	CDD:290638
		I-set	346..420	CDD:254352	16/103 (16%)
		Ig	360..425	CDD:299845	14/91 (15%)
		Ig5_KIRREL3-like	428..524	CDD:143235	28/108 (26%)
		IG_like	435..524	CDD:214653	26/101 (26%)
dpr12	NP_652462.3	IG	86..183	CDD:214652	14/96 (15%)
		Ig_3	193..271	CDD:404760	23/80 (29%)
		Ig strand B	204..208	CDD:409353	0/3 (0%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810