DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rst and dpr17

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	58/266 - (21%)
Similarity:	98/266 - (36%)	Gaps:	62/266 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 TAVVGARVTLPCRVIN-KQGTLQWTKDDFGLGTSRDLSGF---ERYAMVGSDEEGDY--SLDIYP 96
            ||.:|....:||::.. ....:.|.:.......|.|.:.|   ||:..: ..|:.||  ||.|..
  Fly   416 TAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSI-YQEDHDYTWSLQIKY 479

  Fly    97 VMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVI-YATEDRKVEIECVSVGG 160
            |...|...|:||::..|:....:.      ..:|.|:...|  ||.. :.....||.:.|:..|.
  Fly   480 VEPSDAGWYECQMATEPKLSAKVH------LQIVKPKTELI--GDQSRFVKAGSKVALHCIVRGT 536

  Fly   161 -KPAAEITWIDGLGNVLTDNIE----YTVI------PLPDQRRFTAKSVLRLTPKKEHHNTNFSC 214
             .|...|.|..|...: :|:.|    ||.:      .:.|.:......::.|..|::  :.|::|
  Fly   537 LDPPKYIIWFRGQKKI-SDSDERTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRKED--SGNYTC 598

  Fly   215 QAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVE------ 273
            |..|       |..:.|::..                   :.|....|..|||.:|..:
  Fly   599 QPSN-------SVSVSVDLHV-------------------LSGEYSASAIMSTAARTTKGGRSTC 637

  Fly   274 HSQVRL 279
            ||.:.|
  Fly   638 HSTLGL 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653	23/97 (24%)
		Ig	42..114	CDD:299845	20/77 (26%)
		C2-set_2	135..225	CDD:285423	22/101 (22%)
		Ig_3	265..329	CDD:290638	7/21 (33%)
		I-set	346..420	CDD:254352
		Ig	360..425	CDD:299845
		Ig5_KIRREL3-like	428..524	CDD:143235
		IG_like	435..524	CDD:214653
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	20/75 (27%)
		Ig	415..507	CDD:299845	23/97 (24%)
		IG_like	521..612	CDD:214653	21/100 (21%)
		IGc2	524..605	CDD:197706	20/90 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810