DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rst and dpr10

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	71/335 - (21%)
Similarity:	101/335 - (30%)	Gaps:	133/335 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PQDQTAVVGARVTLPCRV-----------------INKQGTLQWTKDD-FGLGTSRDLSGFERYA 80
            |::.|::||....|.|||                 |...||..:|.|. |.....||:.
  Fly    60 PRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDID------ 118

  Fly    81 MVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTV--LVPPEAPKITQ---- 139
                    :::|.|......|...|:||:|..|     :||....|.:  |:..|...|.|
  Fly   119 --------EWTLQIKWAQQRDAGVYECQISTQP-----VRSYSVNLNIVDLIDAETSDIMQQYYN 170

  Fly   140 GDVIYATEDRKVE------------IECVSV------GG---------------------KPAAE 165
            .|..|..|:|..:            |:.|:|      ||                     :|...
  Fly   171 DDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTH 235

  Fly   166 ITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIR 230
            |.|.. ...||::......:.....:....||:|.:......|:..:||...||     ..|.||
  Fly   236 IFWYH-QDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNT-----EIASIR 294

  Fly   231 VEV-----------KYAPKV---------------KVNVMGSL----------------PGGAGG 253
            |.|           ..||..               .|.|:.::                .||.||
  Fly   295 VHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQAVRVISTMVAALVLLEACSSLLLQSGGGGG 359

  Fly   254 SVGG---AGG 260
            ..||   |||
  Fly   360 CPGGGSPAGG 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653	27/115 (23%)
		Ig	42..114	CDD:299845	20/89 (22%)
		C2-set_2	135..225	CDD:285423	24/132 (18%)
		Ig_3	265..329	CDD:290638
		I-set	346..420	CDD:254352
		Ig	360..425	CDD:299845
		Ig5_KIRREL3-like	428..524	CDD:143235
		IG_like	435..524	CDD:214653
dpr10	NP_729591.1	Ig	63..143	CDD:299845	22/93 (24%)
		IG_like	210..297	CDD:214653	17/92 (18%)
		IGc2	217..287	CDD:197706	11/70 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810