DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rst and dpr13

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	75/271 - (27%)
Similarity:	110/271 - (40%)	Gaps:	67/271 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 TAVVGARVTLPCRVIN-KQGTLQW-TKDDF-----GLGTSRDLSGFERYAMVGSDEEGDYSLDIY 95
            |..:||...:||.|.: .:|.:.| .|.|:     ||.|   .|..||::........|::|.|.
  Fly   186 TTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTT---YSSDERFSATHLKHSEDWTLQIK 247

  Fly    96 PVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEA-PKITQGDVIYATEDRKVEIECVSVG 159
            .|.|.|...|:||||..|.     .|.|..|:|:   || .:||...:.|.|....:.::|..|.
  Fly   248 FVQLRDAGVYECQVSTHPP-----TSIFLHLSVV---EARAEITGPPIRYLTPGSTLRLQCRVVQ 304

  Fly   160 GKPAAE-ITW----------IDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFS 213
            ...|:| |.|          ||...||.|:         ||.:    .|.|.:...:..|:.||:
  Fly   305 NTEASEYIFWYHDNRMINYDIDRGINVSTE---------PDFQ----SSELTIQRTRREHSGNFT 356

  Fly   214 CQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGA-GGSVGGA---GGGSVHM-----STGS 269
            |.|.||     :.|.:.|.:         ..|..|... .|.|||:   ....:||     ::|.
  Fly   357 CVASNT-----QPASVLVHI---------FKGDNPAAMYHGHVGGSTKTTQSQLHMIMIIIASGY 407

  Fly   270 RIVEHSQVRLE 280
            ||. |:.|.::
  Fly   408 RIF-HTSVYMK 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653	32/98 (33%)
		Ig	42..114	CDD:299845	26/78 (33%)
		C2-set_2	135..225	CDD:285423	26/100 (26%)
		Ig_3	265..329	CDD:290638	6/21 (29%)
		I-set	346..420	CDD:254352
		Ig	360..425	CDD:299845
		Ig5_KIRREL3-like	428..524	CDD:143235
		IG_like	435..524	CDD:214653
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	31/97 (32%)
		IG_like	182..262	CDD:214653	25/78 (32%)
		IG_like	285..362	CDD:214653	22/89 (25%)
		IGc2	292..361	CDD:197706	20/81 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810