DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rst and dpr19

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	89/423 - (21%)
Similarity:	141/423 - (33%)	Gaps:	120/423 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLLLATI---VGMVRSSPYTSYQNQRFAMEPQDQTAVV---GARVTLPCRV-INKQGTLQW-TKD 63
            ||||::.   ||.:.||........:.....::.|.|:   |....|||.| :|...|:.| .:.
  Fly    14 LLLLSSTFSDVGKITSSQNHFGNTLQSQFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRK 78

  Fly    64 DF-----GLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTF 123
            ||     ||.|.   |..:|:.:..:...|.:||.|..|..:|...|:||:|..|.....|.
  Fly    79 DFQLLTVGLSTH---SSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIYPTQSIVIE--- 137

  Fly   124 AGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVGGKPAAE----ITWIDGLGNVLTDNIEYTV 184
                :.:.....:|:....::..|...:.:||..   |.|.|    :.|..          :..:
  Fly   138 ----LKIVEAVAEISSAPELHIDETSTLRLECKL---KRATENPAFVFWYH----------DSKM 185

  Fly   185 IPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVN-VMGSLP 248
            |....|..|...|:.:..|:               :.:.|||:.........|....| |:.||.
  Fly   186 INYDSQGGFVVTSIGQSNPQ---------------SGQFYRSSPANKSRATMPMESSNGVLNSLL 235

  Fly   249 GGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRN 313
            |.:...  .|...:|..||.....:|....|     .|||                 .:.:.::.
  Fly   236 GSSDAI--KAPAANVPSSTPYMTQQHQSAYL-----LNPS-----------------VSVLTVKQ 276

  Fly   314 VTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIV 378
            |..: |.....|                   ||| ..||.|:...|     |..|       :..
  Fly   277 VNFR-HAGNYTC-------------------APS-NARPASITVHV-----LRGE-------KTA 308

  Fly   379 WIQHPSDRVVGTSTN-------LTFSVSNETAG 404
            .:||.:..::.|.||       :|....|.|:|
  Fly   309 AMQHANRSILDTETNGNGTFGLITLGGLNGTSG 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653	29/105 (28%)
		Ig	42..114	CDD:299845	25/78 (32%)
		C2-set_2	135..225	CDD:285423	13/93 (14%)
		Ig_3	265..329	CDD:290638	10/63 (16%)
		I-set	346..420	CDD:254352	17/66 (26%)
		Ig	360..425	CDD:299845	11/52 (21%)
		Ig5_KIRREL3-like	428..524	CDD:143235
		IG_like	435..524	CDD:214653
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	25/79 (32%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	22/72 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810