DRSC/TRiP Functional Genomics Resources

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Protein Alignment rst and Opcml

DIOPT Version :9

Sequence 1:NP_001284835.1 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:388 Identity:91/388 - (23%)
Similarity:139/388 - (35%) Gaps:90/388 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 TMQLLLLATIVGMVRSSPYTSYQNQRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLG 68
            :::||.|......|||...|      |.....:.|...|...||.|.:.::...:.|......|.
Mouse    18 SLRLLFLVPTGVPVRSGDAT------FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILY 76

  Fly    69 TSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPE 133
            ...|....:...::..:....||:.|..|.:.|:..|.|.|.  .:..|  :::...|.|.|||:
Mouse    77 AGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQ--TDNHP--KTSRVHLIVQVPPQ 137

  Fly   134 APKITQGDVIYATEDRKVEIECVSVGGKPAAEITW-----IDGLGNVLTDNIEYTVIPLPDQRRF 193
            ...|:..  |...|...|.:.|::: |:|...:||     .:|.|.|..|  ||           
Mouse   138 IMNISSD--ITVNEGSSVTLLCLAI-GRPEPTVTWRHLSVKEGQGFVSED--EY----------- 186

  Fly   194 TAKSVLRLTPKKEHHNTNFSCQAQN-TADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGG 257
                 |.::..|...:..:.|.|.| .|....|  |:::.|.|.|.:      |.....|.|||.
Mouse   187 -----LEISDIKRDQSGEYECSALNDVAAPDVR--KVKITVNYPPYI------SKAKNTGVSVGQ 238

  Fly   258 AGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPI---IGGQKTEMVIRNVTRKFH 319
            .|                  .|.|.|.|.|. ..::||..|..:   :.|.:.|...|..|..|.
Mouse   239 KG------------------ILSCEASAVPM-AEFQWFKEDTRLATGLDGVRIENKGRISTLTFF 284

  Fly   320 DAIVK------CEVQNSVGKSEDSETL-DISYAPSFRQRPQSMEADVGSVV--------SLTC 367
            :...|      |...|.:|.:..|.|| :||        |.|..|..|:|:        :|.|
Mouse   285 NVSEKDYGNYTCVATNKLGNTNASITLYEIS--------PSSAVAGPGAVIDGVNSASRALAC 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rstNP_001284835.1 IG_like 34..130 CDD:214653 19/95 (20%)
Ig 42..114 CDD:299845 15/71 (21%)
C2-set_2 135..225 CDD:285423 21/95 (22%)
Ig_3 265..329 CDD:290638 15/72 (21%)
I-set 346..420 CDD:254352 7/30 (23%)
Ig 360..425 CDD:299845 4/16 (25%)
Ig5_KIRREL3-like 428..524 CDD:143235
IG_like 435..524 CDD:214653
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 18/91 (20%)
Ig strand A' 44..49 CDD:409353 1/4 (25%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 1/5 (20%)
Ig strand C 64..70 CDD:409353 1/5 (20%)
CDR2 71..83 CDD:409353 2/11 (18%)
Ig strand C' 72..76 CDD:409353 0/3 (0%)
Ig strand C' 80..83 CDD:409353 1/2 (50%)
FR3 84..118 CDD:409353 7/33 (21%)
Ig strand D 87..94 CDD:409353 0/6 (0%)
Ig strand E 97..103 CDD:409353 2/5 (40%)
Ig strand F 110..118 CDD:409353 2/7 (29%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 2/10 (20%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 135..206 CDD:404760 21/91 (23%)
Ig strand A 135..138 CDD:409353 2/2 (100%)
Ig strand A' 144..148 CDD:409353 1/5 (20%)
Ig strand B 151..160 CDD:409353 2/8 (25%)
Ig strand C 165..170 CDD:409353 1/4 (25%)
Ig strand C' 171..174 CDD:409353 0/2 (0%)
Ig strand F 198..206 CDD:409353 2/7 (29%)
Ig_3 223..300 CDD:404760 22/101 (22%)
putative Ig strand A 224..230 CDD:409353 2/11 (18%)
Ig strand B 240..244 CDD:409353 2/21 (10%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 1/3 (33%)
Ig strand F 293..298 CDD:409353 1/4 (25%)
Ig strand G 306..309 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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