DRSC/TRiP Functional Genomics Resources

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Protein Alignment rst and Negr1

DIOPT Version :9

Sequence 1:NP_001284835.1 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:284 Identity:66/284 - (23%)
Similarity:103/284 - (36%) Gaps:72/284 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 DYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEI 153
            ||||.|..|.:.||..|.|.|    :.|...|:....|||.|||:...|:....|  .|...|.:
Mouse    94 DYSLQIQNVDVTDDGPYTCSV----QTQHTPRTMQVHLTV
QVPPKIYDISNDMTI--NEGTNVTL 152

  Fly   154 ECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQN 218
            .|::. |||...|:|         .:|.      |..:.|.....|.:..........:.|.|:|
Mouse   153 TCLAT-GKPEPVISW---------RHIS------PSAKPFENGQYLDIYGITRDQAGEYECSAEN 201

  Fly   219 TADRTYRSA-KIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECR 282
              |.::... |:||.|.:||.::....|::..|..|.:...|.|                     
Mouse   202 --DVS
FPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAG--------------------- 243

  Fly   283 ADANPSDVRYRWFINDEPIIGGQ----------KTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDS 337
              ..|.  .:.|:..::.:..||          ::.:.:.|||:: |.....|...|.:|.:..|
Mouse   244 --VPPP--AFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQE-HFGNYTCVAANKLGTTNAS 303

  Fly   338 ETLD-----------ISYAPSFRQ 350
            ..|:           .|.|||..|
Mouse   304 LPLNQIIEPTTSSPVTSPAPSTAQ 327

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rstNP_001284835.1 IG_like 34..130 CDD:214653 16/40 (40%)
Ig 42..114 CDD:299845 11/24 (46%)
C2-set_2 135..225 CDD:285423 18/89 (20%)
Ig_3 265..329 CDD:290638 9/73 (12%)
I-set 346..420 CDD:254352 3/5 (60%)
Ig 360..425 CDD:299845
Ig5_KIRREL3-like 428..524 CDD:143235
IG_like 435..524 CDD:214653
Negr1XP_036019026.1 FR1 38..55 CDD:409353
Ig strand A' 40..46 CDD:409353
IG_like 41..129 CDD:214653 14/38 (37%)
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353 11/24 (46%)
Ig strand D 84..91 CDD:409353
Ig strand E 94..100 CDD:409353 4/5 (80%)
Ig strand F 107..115 CDD:409353 4/11 (36%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 2/8 (25%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig strand A' 139..144 CDD:409353 0/4 (0%)
IGc2 146..204 CDD:197706 16/75 (21%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 2/13 (15%)
Ig strand C' 170..172 CDD:409353 0/7 (0%)
Ig strand E 180..186 CDD:409353 1/5 (20%)
Ig strand F 193..200 CDD:409353 1/6 (17%)
Ig_3 219..295 CDD:404760 15/101 (15%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 0/3 (0%)
Ig strand F 288..293 CDD:409353 1/4 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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