DRSC/TRiP Functional Genomics Resources

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Protein Alignment rst and Igsf9

DIOPT Version :9

Sequence 1:NP_001284835.1 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster
Sequence 2:NP_001100667.1 Gene:Igsf9 / 304982 RGDID:1304566 Length:1179 Species:Rattus norvegicus


Alignment Length:841 Identity:170/841 - (20%)
Similarity:268/841 - (31%) Gaps:269/841 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MLHTMQLLLLATIVGMVRSSPYTSYQNQRFAMEPQDQTAV--VGARVTLPCRVINKQG-----TL 58
            |:..::|.:|:.|:.          |......:|:..:.|  .|....|.|.::...|     .:
  Rat     1 MIWCLRLTILSLILS----------QGADGRRKPEVVSVVGRAGESAVLGCDLLPPAGRPPLHVI 55

  Fly    59 QWTKDDFGLGTSRDLSGFERYAMVGSDEEGDY----------SLDIYPVMLDDDARYQCQV---- 109
            :|.:..|.|..      |.::.:.....:.||          ||.|..:.::|...|:|:|    
  Rat    56 EWLRFGFLLPI------FIQFGLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLD 114

  Fly   110 SPGPEGQPAIRSTFAGLTVLVPP---EAPKITQGDVIYATEDRKVEIECVSVGGKPAAEITWI-- 169
            ...|| |.....::..|||..||   |.|.:    |:...|...|.:.||:: |.|...:||.  
  Rat   115 QHSPE-QDFANGSWVHLTVNSPPQFQETPPL----VLEVKELEAVTLRCVAL-GSPQPYVTWKFR 173

  Fly   170 -----DGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKI 229
                 .|.|.|...|....:      ||....|.           .:::|||.:|......:.::
  Rat   174 GQDLGKGQGQVQVRNGTLWI------RRVERGSA-----------GDYTCQASSTEGSVTHTTQL 221

  Fly   230 RVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQ-VRLECRADANPSDVRYR 293
            .|   ..|.|.|                       :...:..|..|| |.|.|||:|.|:::.|.
  Rat   222 LV---LGPPVIV-----------------------VPPNNNTVNASQDVSLACRAEAYPANLTYS 260

  Fly   294 WFINDEPIIGGQKTEMVIR---------NVTRKFHDAIVKCEVQNSVGKSED-SETLDISYAPSF 348
            ||.:...:....:.:..:|         ..|:........|...|....... |..|.:.|....
  Rat   261 WFQDRINVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFPHPPSASAYLTVLYPAQV 325

  Fly   349 RQRPQSMEADVGSVVSLTCEVDSNPQPEIV-WIQHPS----DRVVGTST----NLTFSVSNETA- 403
            ...|......:|....:.|.|.:||....| |.:...    |:..|.|.    :|..::.||.| 
  Rat   326 TVMPPETPLPIGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLVIALGNEDAL 390

  Fly   404 GRYYCKA-NVPGYAEISADAYVYLKGSPAIGSQRTQ--YGLVGDTARIECFASSVPRARHVSWTF 465
            |.|.|.. |..|.|..|....|.||..||...|..:  :..||....|.|.|...| ...|||..
  Rat   391 GEYSCTPYNSLGTAGSSPVTRVLLKAPPAFIDQPKEEYFQEVGRDLLIPCSARGDP-PPIVSWAK 454

  Fly   466 NGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVAEIQLQAKKSVS 530
            .|:.:..::..|.:           ::||:|......:|::.|:.    .|.||.:.:..  :|.
  Rat   455 VGRGLQGQAQVDSN-----------NSLILRPLTKEAHGRWECSA----RNAVAHVTIST--NVY 502

  Fly   531 LLMT---IVGGISVVAFLLVLTILVVVYIKCKKRTKLPPADVISEHQITKNGGVSCKLEPGDRTS 592
            :|.|   :|..:|||                    .||.             |.:...|||    
  Rat   503 VLGTSPHVVTNVSVV--------------------PLPK-------------GANVSWEPG---- 530

  Fly   593 NYSDLKVDISGGYVPYGDYSTHYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQH 657
                    ..|||:.  .:|..|:|                            |.::..::||..
  Rat   531 --------FDGGYLQ--RFSVWYTP----------------------------LAKRPDRAHHDW 557

  Fly   658 HTQTTTLPMTFLTNSSGGSLTGSIIGSREIRQDNGLPSLQSTT-----------------ASVVS 705
            .:....:..|.|.                      :|.||:.|                 :.:|.
  Rat   558 VSLAVPMGATHLL----------------------VPGLQAYTQYQFSVLAQNKLGSGPFSEIVL 600

  Fly   706 SSPNGSCSNQSTTAATTTTTHVVVPSSMALSVDPRYSAIYGNPYLRSSNSSLL--PPPTAV 764
            |.|.|    ..||.|        ||......:.|..|...|...:|:....||  .||..:
  Rat   601 SIPEG----LPTTPA--------VPRLPPTEMPPPLSPPRGLVAVRTPRGVLLHWDPPELI 649

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rstNP_001284835.1 IG_like 34..130 CDD:214653 25/116 (22%)
Ig 42..114 CDD:299845 17/90 (19%)
C2-set_2 135..225 CDD:285423 21/96 (22%)
Ig_3 265..329 CDD:290638 16/73 (22%)
I-set 346..420 CDD:254352 21/84 (25%)
Ig 360..425 CDD:299845 21/75 (28%)
Ig5_KIRREL3-like 428..524 CDD:143235 22/97 (23%)
IG_like 435..524 CDD:214653 20/90 (22%)
Igsf9NP_001100667.1 IG 28..110 CDD:214652 17/87 (20%)
Ig strand A 136..139 CDD:409353 1/2 (50%)
IG_like 143..223 CDD:214653 20/101 (20%)
Ig strand A' 145..148 CDD:409353 1/2 (50%)
Ig strand B 154..161 CDD:409353 3/6 (50%)
Ig strand C 167..172 CDD:409353 2/4 (50%)
Ig strand C' 175..177 CDD:409353 0/1 (0%)
Ig strand D 183..187 CDD:409353 1/3 (33%)
Ig strand E 189..193 CDD:409353 0/3 (0%)
Ig strand F 202..210 CDD:409353 3/7 (43%)
Ig strand G 213..223 CDD:409353 0/9 (0%)
Ig_3 226..305 CDD:404760 19/101 (19%)
putative Ig strand A 226..230 CDD:409353 2/3 (67%)
putative Ig strand A' 235..239 CDD:409353 0/3 (0%)
putative Ig strand B 241..251 CDD:409353 6/9 (67%)
putative Ig strand C' 267..270 CDD:409353 0/2 (0%)
putative Ig strand D 279..282 CDD:409353 1/2 (50%)
putative Ig strand E 284..290 CDD:409353 0/5 (0%)
putative Ig strand F 297..305 CDD:409353 1/7 (14%)
putative Ig strand G 310..319 CDD:409353 2/8 (25%)
Ig 322..407 CDD:416386 21/84 (25%)
Ig strand A' 324..328 CDD:409353 0/3 (0%)
Ig strand B 333..347 CDD:409353 2/13 (15%)
Ig strand C 353..359 CDD:409353 2/5 (40%)
Ig strand C' 362..364 CDD:409353 0/1 (0%)
Ig strand D 371..374 CDD:409353 1/2 (50%)
Ig strand E 378..382 CDD:409353 1/3 (33%)
Ig strand F 391..399 CDD:409353 3/7 (43%)
Ig 418..503 CDD:416386 23/102 (23%)
Ig strand A 418..421 CDD:409353 2/2 (100%)
Ig strand A' 427..430 CDD:409353 0/2 (0%)
Ig strand B 436..443 CDD:409353 2/6 (33%)
Ig strand C 449..454 CDD:409353 3/4 (75%)
Ig strand C' 457..459 CDD:409353 0/1 (0%)
Ig strand D 462..466 CDD:409353 0/3 (0%)
Ig strand E 469..473 CDD:409353 1/3 (33%)
Ig strand F 482..490 CDD:409353 2/11 (18%)
Ig strand G 493..503 CDD:409353 2/11 (18%)
FN3 508..599 CDD:238020 25/187 (13%)
FN3 625..715 CDD:238020 7/25 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 766..807
PHA03247 <777..1062 CDD:223021
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..846
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 869..895
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..979
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079
PDZ-binding. /evidence=ECO:0000250 1177..1179
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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