DRSC/TRiP Functional Genomics Resources

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Protein Alignment rst and Dscam4

DIOPT Version :9

Sequence 1:NP_001284835.1 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster
Sequence 2:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster


Alignment Length:1089 Identity:209/1089 - (19%)
Similarity:336/1089 - (30%) Gaps:402/1089 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 IVGMVRSSPYTSYQNQRFAMEPQDQT-------------AVVGARVTLPCRVINKQG----TLQW 60
            :.|.|:.|   :|..:....||:...             .|:..:.||||..   ||    |.:|
  Fly   211 LTGEVQIS---TYPGRIIVTEPKGMVQPRINVEKHSMRHVVLNGQTTLPCIA---QGHPVPTYRW 269

  Fly    61 TKDDFGLGTSRDLSGFERYAMVGS----------DEEGDY---------------SL-------- 92
            .|::........||  ||..:|.:          ::.|.|               ||        
  Fly   270 FKEENEQLLPLQLS--ERITIVSAGLLKITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTA 332

  Fly    93 ----DIYPVMLDDDARYQCQVSPGP--------EGQPAIRSTFAGLTVLVPP----------EAP 135
                .:..|.:|.||::||.||..|        :|:|.:|..  .:.:|..|          |.|
  Fly   333 HLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDN--RVEILTDPPRLIIKKVQKEDP 395

  Fly   136 KITQ------------------GD----VIYATEDR------KVEIECVSVGGKPAAEITW-IDG 171
            .:.|                  ||    ::|...::      .|.::||:. |.|..:.|| :||
  Fly   396 GMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSEQTLQPGPTVSLKCVAT-GNPLPQFTWSLDG 459

  Fly   172 LGNVLTDNIEYTVIPLPDQRRFTAK----------SVLRLTPKKEHHNTNFSCQAQNTADRTYRS 226
                         .|:||..||...          |.:.::..||.....::|.|||...:...|
  Fly   460 -------------FPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHS 511

  Fly   227 AKIRV----EVKYAPKVKVNVMGSLPGGAGGS-------VGGAGGGSVH---------------- 264
            ||:.:    .::..||:.         |..||       |.|.....:|                
  Fly   512 AKVNIYGLPYIREMPKIT---------GISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRA 567

  Fly   265 MSTGSRIVEHSQVRLE------------------------------------------------- 280
            .:.|:.|:|..| |||                                                 
  Fly   568 YNNGTLIIEQLQ-RLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAI 631

  Fly   281 -CRADANPSDVRYRWFINDEPIIG-GQK---------TEMVIRNVTRKFHDAIVKCEVQNSVGKS 334
             |:.......|.:||..|.:|:|| |.:         ..:||.:::.. |.....|...|..|..
  Fly   632 SCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSD-HSGNYTCIASNVAGTE 695

  Fly   335 EDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVW--------------IQHPSD 385
            ..:..|.::..|.:...|:...|..|:.|.|.|:....|.|.|.|              :..|:.
  Fly   696 RFTVPLTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTV 760

  Fly   386 RVVGTSTNLTFSVSNETAGRYYCKA--NV-PGYAEISADAYVYLK-GSPAIGSQRTQYGLV--GD 444
            ::....|.....:|.|:.|.:.|:|  |: .|.:::     ::|| ..||....:|:...|  |.
  Fly   761 QLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKV-----IFLKVNVPAHFQTKTKQISVAKGK 820

  Fly   445 TARIECFASSVPRARHVSWTFNG-QEISSES-GHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYN 507
            ...::|.... .......|.... |:...|| ...|:|....:..|:.|.|.|..:.....|.|.
  Fly   821 QVHVQCNVQG-DNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYI 884

  Fly   508 CTVVNDYGNDVAEIQL--------------QAKKSVSLLMT------------------------ 534
            |...|.:|.|...|||              .:::|.||.:|                        
  Fly   885 CQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSRSLQLTWSQPFAGNSPIEEYHIYYKQISDI 949

  Fly   535 -------IVGGISVVAFLLVLTILVVVYIKCKKRTKLPPAD------VISEHQITKNGGVSCKLE 586
                   .:.|...|..:..|......:|:.....||..::      |.:..::.....::.:.|
  Fly   950 WQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAE 1014

  Fly   587 PGDRTSNY-------SDLKVDISGGYVPYGDYSTHYSP------PPQYLT--TCSTKSN-GSSTI 635
            |...|..:       .|....|..||  |..|....:|      |.|..:  |...:|: |..|:
  Fly  1015 PKSSTEIFVTWDAPERDHWNGILLGY--YVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETV 1077

  Fly   636 MQNNH---QNQLQLQQQQQQSHHQHHTQTTTLPMTFLTNSSGGSLTGSIIGSR---------EIR 688
            :.|.:   |..:.:|....|.......:.....|..:.:|...|....::||.         :|.
  Fly  1078 LANLNKFTQYHVIVQAYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDID 1142

  Fly   689 QDNG-----------LPSLQSTTASVVSSSPNGSCSNQSTTAA-----TTTT------------- 724
            ..||           :..|..|...||.|      :||..|..     |..|             
  Fly  1143 GQNGKIKGYKVFYISVDELYETDPEVVKS------TNQYVTIENLRKYTNYTVWVLAYTKVGDGM 1201

  Fly   725 --------THVVVPSS-MALSVDPRYSAIYGNPYLRSSNS----SLLPP 760
                    ||..|||: .|:...|            :|:|    |.|||
  Fly  1202 KTKPFYCRTHEDVPSAPQAIKAIP------------ASSSKIIISWLPP 1238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rstNP_001284835.1 IG_like 34..130 CDD:214653 32/157 (20%)
Ig 42..114 CDD:299845 27/120 (23%)
C2-set_2 135..225 CDD:285423 26/128 (20%)
Ig_3 265..329 CDD:290638 20/123 (16%)
I-set 346..420 CDD:254352 20/90 (22%)
Ig 360..425 CDD:299845 17/81 (21%)
Ig5_KIRREL3-like 428..524 CDD:143235 25/113 (22%)
IG_like 435..524 CDD:214653 23/106 (22%)
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386 19/95 (20%)
Ig strand A 235..238 CDD:409353 0/2 (0%)
Ig strand A' 244..248 CDD:409353 0/3 (0%)
Ig strand B 251..258 CDD:409353 3/6 (50%)
Ig strand C 266..271 CDD:409353 2/4 (50%)
Ig strand C' 276..279 CDD:409353 0/2 (0%)
Ig strand D 285..289 CDD:409353 1/3 (33%)
Ig strand E 292..298 CDD:409353 0/5 (0%)
Ig strand F 305..313 CDD:409353 2/7 (29%)
Ig strand G 316..326 CDD:409353 2/9 (22%)
IgC2_3_Dscam 329..417 CDD:409549 17/89 (19%)
Ig strand B 347..351 CDD:409549 1/3 (33%)
Ig strand C 360..364 CDD:409549 0/3 (0%)
Ig strand E 383..387 CDD:409549 0/3 (0%)
Ig strand F 397..402 CDD:409549 1/4 (25%)
Ig strand G 410..413 CDD:409549 0/2 (0%)
IgI_4_Dscam 422..516 CDD:409548 25/107 (23%)
Ig strand B 439..443 CDD:409548 1/3 (33%)
Ig strand C 452..456 CDD:409548 1/3 (33%)
Ig strand E 482..486 CDD:409548 1/3 (33%)
Ig strand F 496..501 CDD:409548 1/4 (25%)
Ig strand G 509..512 CDD:409548 0/2 (0%)
IgI_5_Dscam 520..607 CDD:409550 15/96 (16%)
Ig strand B 536..540 CDD:409550 0/3 (0%)
Ig strand C 549..553 CDD:409550 1/3 (33%)
Ig strand E 571..575 CDD:409550 1/3 (33%)
Ig strand F 586..591 CDD:409550 0/4 (0%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 16/93 (17%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 0/3 (0%)
Ig strand B 627..636 CDD:409353 1/8 (13%)
Ig strand C 641..648 CDD:409353 3/6 (50%)
Ig strand C' 650..652 CDD:409353 0/1 (0%)
Ig strand D 659..664 CDD:409353 0/4 (0%)
Ig strand E 668..675 CDD:409353 2/6 (33%)
Ig strand F 682..690 CDD:409353 1/7 (14%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 21/99 (21%)
Ig strand B 724..728 CDD:409546 2/3 (67%)
Ig strand C 737..741 CDD:409546 1/3 (33%)
Ig strand E 766..770 CDD:409546 1/3 (33%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/7 (0%)
Ig 818..904 CDD:416386 21/86 (24%)
putative Ig strand B 820..827 CDD:409353 0/6 (0%)
putative Ig strand C 835..841 CDD:409353 1/5 (20%)
putative Ig strand C' 853..856 CDD:409353 0/2 (0%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 3/5 (60%)
putative Ig strand F 881..889 CDD:409353 3/7 (43%)
putative Ig strand G 892..902 CDD:409353 5/9 (56%)
FN3 906..999 CDD:238020 11/92 (12%)
FN3 1006..1110 CDD:238020 20/105 (19%)
fn3 1117..1203 CDD:394996 17/91 (19%)
FN3 1215..1307 CDD:238020 10/36 (28%)
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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