DRSC/TRiP Functional Genomics Resources

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Protein Alignment rst and Ncam1

DIOPT Version :9

Sequence 1:NP_001284835.1 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster
Sequence 2:XP_038936733.1 Gene:Ncam1 / 24586 RGDID:67378 Length:1136 Species:Rattus norvegicus


Alignment Length:936 Identity:185/936 - (19%)
Similarity:305/936 - (32%) Gaps:280/936 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 VGARVTLPCRVINKQGTLQWTKDDF------GLGTSRDLSGF-----------ERYAMVGSDEEG 88
            :|..|:|...::..||.:...:..|      |....:|:|.|           :|.::|.:|::.
  Rat    14 LGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDS 78

  Fly    89 DYSLDIYPVMLDDDARYQCQVS--PGPEGQPAIR-STFAGLTVLVPPEAPKITQGDVIYATEDRK 150
            . :|.||...:||...|:|.|:  .|.:.:..:. ..|..|.....|...:..:|      ||  
  Rat    79 S-TLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEG------ED-- 134

  Fly   151 VEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQ 215
            ..|.|..|...|...|....|...:|..::.:.|:         :.:.|::...|:.....:.|:
  Rat   135 AVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVL---------SNNYLQIRGIKKTDEGTYRCE 190

  Fly   216 AQNTADRTYRSAKIRVEVKYAPKVK-----VNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHS 275
            .:..|........|:|.|...|.|:     ||...:|            |.|             
  Rat   191 GRILARGEINFKDIQVIVNVPPTVQARQSIVNATANL------------GQS------------- 230

  Fly   276 QVRLECRADANPSDVRYRWFINDEP-----------IIGGQKTEMVIRNVTRKFHDAIVKCEVQN 329
             |.|.|.||..| :....|..:.||           |.....:|:.||||. |..:|...|..:|
  Rat   231 -VTLVCDADGFP-EPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVD-KNDEAEYVCIAEN 292

  Fly   330 SVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTS--- 391
            ..|:.:.|..|.:...|...........::...|:||||...:|.|.|.|  ..|.|.:.:.   
  Rat   293 KAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITW--RTSTRNISSEEKA 355

  Fly   392 -----------------------TNLTF-SVSNETAGRYYCKA-NVPGYAEISADAYVYLKGSPA 431
                                   ::||. |:....||.|.|.| |..|  :.|...|:.::.:|.
  Rat   356 SWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG--QDSQSMYLEVQYAPK 418

  Fly   432 IGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSESGHDYS-ILVDAVPGGVKSTLII 495
            :......|...|:...|.|...:.|.|. :||..:||.:.|.   :|| |.:...|..  |.|.:
  Rat   419 LQGPVAVYTWEGNQVNITCEVFAYPSAT-ISWFRDGQLLPSS---NYSNIKIYNTPSA--SYLEV 477

  Fly   496 RDSQAYHYGKYNCTVVNDYGNDVAE---IQLQAKKSVSLLMT---------------IVGGISVV 542
            .......:|.||||.||..|.:..|   :|.....|.|:...               ..||:.::
  Rat   478 TPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPIL 542

  Fly   543 AFLLVLTIL-------------------VVVYIKCKKRTK------------LPPADVISE---- 572
            .:......|                   :|..:..|..|:            |......:|    
  Rat   543 KYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGEISAATEFKTQ 607

  Fly   573 --HQITKNGGVSC-KLEPGDRTSNYSDLKVDI----SGGYVPYGDYSTHYSPPPQYLTTCSTK-- 628
              |.....|..|. ||| |....:.:.:||::    .||           ||...||.....|  
  Rat   608 PVHSPPPQGEPSAPKLE-GQMGEDGNSIKVNLIKQDDGG-----------SPIRHYLVKYRAKLA 660

  Fly   629 ---------SNGSSTIMQNN------HQNQLQLQQQQQQSHHQHHT-QTTTLPMTFLTNSS--GG 675
                     .:||..:|..:      ::..:..:.||.:|...|.. :|:..|.....|.|  .|
  Rat   661 SEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAG 725

  Fly   676 SLTGSIIG------------------------------------------SREIRQDNGLPSLQS 698
            ..||:|:|                                          .:::.:.....|...
  Rat   726 LSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDE 790

  Fly   699 TTASVV------SSSPNGSCS-----NQST-------TAATTTTTHVVVPSSMAL-----SVDPR 740
            :...:|      ..:||....     |::|       .|.||.|...::||...:     ::...
  Rat   791 SKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITET 855

  Fly   741 YSAIYGNPYLRSS--NSSLLPPPTAV 764
            ::....:|...::  .||:.||.|.|
  Rat   856 FATAQNSPTSETTTLTSSIAPPATTV 881

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rstNP_001284835.1 IG_like 34..130 CDD:214653 24/108 (22%)
Ig 42..114 CDD:299845 22/90 (24%)
C2-set_2 135..225 CDD:285423 15/89 (17%)
Ig_3 265..329 CDD:290638 18/74 (24%)
I-set 346..420 CDD:254352 22/101 (22%)
Ig 360..425 CDD:299845 23/92 (25%)
Ig5_KIRREL3-like 428..524 CDD:143235 28/99 (28%)
IG_like 435..524 CDD:214653 27/92 (29%)
Ncam1XP_038936733.1 IgI_1_NCAM-1 20..116 CDD:409451 20/96 (21%)
Ig strand B 37..41 CDD:409451 1/3 (33%)
Ig strand C 51..55 CDD:409451 2/3 (67%)
Ig strand E 79..83 CDD:409451 1/4 (25%)
Ig strand F 93..98 CDD:409451 2/4 (50%)
Ig strand G 107..110 CDD:409451 0/2 (0%)
IG_like 124..190 CDD:214653 14/82 (17%)
Ig strand B 135..139 CDD:409353 1/3 (33%)
Ig strand C 148..152 CDD:409353 1/3 (33%)
Ig strand E 172..176 CDD:409353 1/3 (33%)
Ig strand F 186..191 CDD:409353 1/4 (25%)
IgI_3_NCAM-1 211..308 CDD:143207 29/124 (23%)
Ig strand B 231..235 CDD:143207 2/3 (67%)
Ig strand C 244..248 CDD:143207 0/3 (0%)
Ig strand E 271..275 CDD:143207 1/3 (33%)
Ig strand F 285..290 CDD:143207 1/4 (25%)
Ig strand G 298..301 CDD:143207 0/2 (0%)
IgI_NCAM-1 307..413 CDD:143277 24/109 (22%)
Ig strand B 326..330 CDD:143277 2/3 (67%)
Ig strand C 339..343 CDD:143277 2/5 (40%)
Ig strand E 379..383 CDD:143277 1/3 (33%)
Ig strand F 393..398 CDD:143277 2/4 (50%)
Ig strand G 406..409 CDD:143277 1/2 (50%)
Ig_3 422..494 CDD:404760 22/77 (29%)
Ig strand B 433..437 CDD:409353 1/3 (33%)
Ig strand C 446..450 CDD:409353 1/4 (25%)
Ig strand E 473..477 CDD:409353 2/3 (67%)
Ig strand F 487..492 CDD:409353 3/4 (75%)
FN3 509..606 CDD:238020 10/96 (10%)
fn3 619..701 CDD:394996 19/93 (20%)
Herpes_BLLF1 <842..1133 CDD:282904 7/40 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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