DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rst and zig-4

DIOPT Version :9

Sequence 1:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	45/187 - (24%)
Similarity:	70/187 - (37%)	Gaps:	67/187 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 MEADVGS-VVSLTCEVDSN--PQPEIVWIQHPSDRVVGTSTNLTFSVSNETAGRYYCKANVPGYA 416
            |.|::.| ||:|..|:|:|  ..|..:.|..|.:                       .|.:||
Worm    20 MHAEMHSAVVTLANEIDTNYLTSPAKIKIVAPLE-----------------------SALIPG-- 59

  Fly   417 EISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEI--SSESGHDYS 479
                                      |:|.::.|...|.|.|. :.|.|||:.|  |:|...:..
Worm    60 --------------------------GETYQLRCDIMSTPAAT-IHWKFNGKLIQGSNELNVEEK 97

  Fly   480 IL------VDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYG--NDVAEIQLQAKKS 528
            :|      ||.  |.|.|.|.|:...|.:.|.|:|...|.:.  ..|||::::.:.|
Worm    98 LLNFGKAIVDT--GIVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGEAS 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rst	NP_001284835.1	IG_like	34..130	CDD:214653
		Ig	42..114	CDD:299845
		C2-set_2	135..225	CDD:285423
		Ig_3	265..329	CDD:290638
		I-set	346..420	CDD:254352	15/67 (22%)
		Ig	360..425	CDD:299845	13/67 (19%)
		Ig5_KIRREL3-like	428..524	CDD:143235	29/105 (28%)
		IG_like	435..524	CDD:214653	29/98 (30%)
zig-4	NP_509335.1	I-set	47..147	CDD:254352	34/153 (22%)
		Ig	65..144	CDD:143165	25/81 (31%)
		IG_like	176..245	CDD:214653
		Ig	<193..238	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900